Comorbidity of osteoporosis and Alzheimer's disease: IsAKT-ing on cellular glucose uptake the missing link?

K Fehsel, J Christl - Ageing Research Reviews, 2022 - Elsevier
Osteoporosis and Alzheimer's disease (AD) are both degenerative diseases. Osteoporosis
often proceeds cognitive deficits, and multiple studies have revealed common triggers that …

Common miRNAs of osteoporosis and fibromyalgia: a review

S Philippe, M Delay, N Macian, V Morel… - International Journal of …, 2023 - mdpi.com
A significant clinical association between osteoporosis (OP) and fibromyalgia (FM) has been
shown in the literature. Given the need for specific biomarkers to improve OP and FM …

A dual role of HIF1α in regulating osteogenesis–angiogenesis coupling

J Shao, S Liu, M Zhang, S Chen, S Gan, C Chen… - Stem Cell Research & …, 2022 - Springer
Objectives The hypoxia-inducible factor 1-α (HIF1α), a key molecule in mediating bone-
vessel crosstalk, has been considered a promising target for treating osteoporosis caused …

Associations between osteoporosis and drug exposure: a post-marketing study of the World Health Organization pharmacovigilance database (VigiBase®)

B Batteux, Y Bennis, S Bodeau, K Masmoudi… - Bone, 2021 - Elsevier
Background Bone remodeling is a complex process, and many conditions (including drug
exposure) lead to osteoporosis. Here, we sought to detect new disproportionality signals for …

Exploring the boost of steaming with wine on Ligustri Lucidi Fructus in treating postmenopausal osteoporosis based on superior “multi-component structure” and iron …

J Jiang, B Zhao, J Xiao, L Shi, W Shang, Y Shu, Z Zhao… - Phytomedicine, 2024 - Elsevier
Background Clinical studies indicated that postmenopausal osteoporosis (PMOP) often
accompanied by iron overload risk factor, which exacerbated bone metabolism disorders …

Network pharmacology-based mechanism prediction and pharmacological validation of Bushenhuoxue formula attenuating postmenopausal osteoporosis in …

C Xia, H Zhu, J Li, H Jin, D Fu - Journal of Orthopaedic Surgery and …, 2023 - Springer
Background Bushenhuoxue (BSHX) formula, a ten-compound herbal decoction, is widely
used to treat postmenopausal osteoporosis (PMOP) in China. However, the mechanism is …

Identifying potential ferroptosis key genes for diagnosis and treatment of postmenopausal osteoporosis through competitive endogenous RNA network analysis

C Huang, Y Li, B Li, X Liu, D Luo, Y Liu, M Wei… - Heliyon, 2024 - cell.com
Objective Postmenopausal osteoporosis (PMOP) is a common systemic metabolic bone
disorder that is owing to the reduced estrogen secretion and imbalance of bone absorption …

ER-β accelerates the process of primary osteoporosis by promoting VEGFA-mediated apoptosis of osteoblasts

Z Xu, P Wang, Z Wang, H Cui, T Gao, Z Wang, Y Liu - Genomics, 2023 - Elsevier
Primary osteoporosis (POP) is a widespread and severe disorder of bone metabolism
characterized by reduced bone mass and destruction of bone structure, frequently inducing …

Angiogenesis and Multiple Sclerosis Pathogenesis: A Glance at New Pharmaceutical Approaches

MT Gentile, G Muto, G Lus, KO Lövblad… - Journal of Clinical …, 2022 - mdpi.com
Multiple sclerosis is a chronic disease of the central nervous system characterized by
demyelination and destruction of axons. The most common form of the disease is the …

Role of miRNA-regulated type H vessel formation in osteoporosis

D Zhang, Y Wang, Z Zhou, L Wang, C Liu… - Frontiers in …, 2024 - frontiersin.org
Osteoporosis (OP) is a chronic systemic bone metabolism disease characterized by
decreased bone mass, microarchitectural deterioration, and fragility fractures. With the …