Bladder overactivity and hyperexcitability of bladder afferent neurons after intrathecal delivery of nerve growth factor in rats

N Yoshimura, NE Bennett, Y Hayashi… - Journal of …, 2006 - Soc Neuroscience
Nerve growth factor (NGF) has been proposed as an important mediator inducing bladder
overactivity under pathological conditions such as spinal cord injury, bladder outlet …

Disruption of bladder epithelium barrier function after spinal cord injury

G Apodaca, S Kiss, W Ruiz, S Meyers… - American Journal …, 2003 - journals.physiology.org
Neural-epithelial interactions are hypothesized to play an important role in bladder function.
We determined whether spinal cord injury (SCI) altered several indicators of urinary bladder …

Urinary nerve growth factor level is increased in patients with interstitial cystitis/bladder pain syndrome and decreased in responders to treatment

HT Liu, P Tyagi, MB Chancellor, HC Kuo - BJU international, 2009 - Wiley Online Library
OBJECTIVE To measure urinary nerve growth factor (NGF) levels in patients with interstitial
cystitis/bladder pain syndrome (IC/BPS), and to evaluate the role of urinary NGF in …

Intravesical resiniferatoxin versus botulinum-A toxin injections for neurogenic detrusor overactivity: a prospective randomized study

A Giannantoni, SM Di Stasi, RL Stephen, V Bini… - The Journal of …, 2004 - Elsevier
PURPOSE:: We investigated the effectiveness and safety of intravesical resiniferatoxin
(Sigma Chemical Co., St. Louis, Missouri) and botulinum-A toxin injections into the detrusor …

[HTML][HTML] Urinary biomarkers in interstitial cystitis/bladder pain syndrome and its impact on therapeutic outcome

HY Lin, JH Lu, SM Chuang, KS Chueh, TJ Juan, YC Liu… - Diagnostics, 2021 - mdpi.com
Interstitial cystitis/bladder pain syndrome (IC/BPS) is defined as a chronic bladder disorder
with suprapubic pain (pelvic pain) and pressure and/or discomfort related to bladder filling …

The involvement of the tetrodotoxin-resistant sodium channel Nav1. 8 (PN3/SNS) in a rat model of visceral pain

N Yoshimura, S Seki, SD Novakovic… - Journal of …, 2001 - Soc Neuroscience
The present study investigated the effect of inhibiting the expression of Nav1. 8 (PN3/SNS)
sodium channels by an antisense oligodeoxynucleotide (ODN) on bladder nociceptive …

[HTML][HTML] A systematic review of the (un) known host immune response biomarkers for predicting recurrence of urinary tract infection

I Sorić Hosman, A Cvitković Roić, L Lamot - Frontiers in medicine, 2022 - frontiersin.org
Recurrent urinary tract infections (rUTI) represent a major healthcare and economic burden
along with a significant impact on patient's morbidity and quality of life, even in the absence …

Animal models in urological disease and sexual dysfunction

G McMurray, JH Casey… - British journal of …, 2006 - Wiley Online Library
There are several conditions associated with dysfunction of the lower urinary tract or which
result in a reduction in the ability to engage in satisfactory sexual function and result in …

Control of urinary bladder function with devices: successes and failures

RA Gaunt, A Prochazka - Progress in brain research, 2006 - Elsevier
The management of urinary tract dysfunction is crucial for the health and well-being of
people with spinal cord injury. Devices, specifically catheters, play an important role in the …

Suppression of detrusor-sphincter dyssynergia by immunoneutralization of nerve growth factor in lumbosacral spinal cord in spinal cord injured rats

S Seki, K Sasaki, Y Igawa, O Nishizawa… - The Journal of …, 2004 - auajournals.org
Purpose: We investigated the effects of intrathecal application of nerve growth factor (NGF)
antibodies (NGF-Abs) and desensitization of C-fiber afferent pathways by capsaicin …