Tachykinins as modulators of the micturition reflex in the central and peripheral nervous system
A Lecci, CA Maggi - Regulatory peptides, 2001 - Elsevier
In the normal urinary bladder, tachykinins (TKs) are expressed in a population of bladder
nociceptors that is sensitive to the excitatory and desensitizing effects of capsaicin (ie …
nociceptors that is sensitive to the excitatory and desensitizing effects of capsaicin (ie …
Neuromodulation of the neural circuits controlling the lower urinary tract
The inability to control timely bladder emptying is one of the most serious challenges among
the many functional deficits that occur after a spinal cord injury. We previously demonstrated …
the many functional deficits that occur after a spinal cord injury. We previously demonstrated …
[HTML][HTML] Optogenetic modulation of urinary bladder contraction for lower urinary tract dysfunction
As current clinical approaches for lower urinary tract (LUT) dysfunction such as
pharmacological and electrical stimulation treatments lack target specificity, thus resulting in …
pharmacological and electrical stimulation treatments lack target specificity, thus resulting in …
Partners in crime: NGF and BDNF in visceral dysfunction
A Coelho, R Oliveira, T Antunes-Lopes… - Current …, 2019 - ingentaconnect.com
Neurotrophins (NTs), particularly Nerve Growth Factor (NGF) and Brain-Derived
Neurotrophic Factor (BDNF), have attracted increasing attention in the context of visceral …
Neurotrophic Factor (BDNF), have attracted increasing attention in the context of visceral …
[HTML][HTML] Autonomic assessment of animals with spinal cord injury: tools, techniques and translation
Study design: Literature review. Objectives: To present a comprehensive overview of
autonomic assessment in experimental spinal cord injury (SCI). Methods: A systematic …
autonomic assessment in experimental spinal cord injury (SCI). Methods: A systematic …
[HTML][HTML] Plasticity of TRPV1-expressing sensory neurons mediating autonomic dysreflexia following spinal cord injury
Spinal cord injury (SCI) triggers profound changes in visceral and somatic targets of sensory
neurons below the level of injury. Despite this, little is known about the influence of injury to …
neurons below the level of injury. Despite this, little is known about the influence of injury to …
Functional, morphological and molecular characterization of bladder dysfunction in streptozotocin‐induced diabetic mice: evidence of a role for L‐type voltage …
LOS Leiria, FZT Monica, F Carvalho… - British journal of …, 2011 - Wiley Online Library
BACKGROUND AND PURPOSE Diabetic cystopathy is one of the most common and
incapacitating complications of diabetes mellitus. This study aimed to evaluate the …
incapacitating complications of diabetes mellitus. This study aimed to evaluate the …
Urotheliogenic modulation of intrinsic activity in spinal cord-transected rat bladders: role of mucosal muscarinic receptors
Y Ikeda, A Kanai - American Journal of Physiology-Renal …, 2008 - journals.physiology.org
We examined the modulation of intrinsic (ie, spontaneous) detrusor contractions by the
urothelium and the lamina propria through optical mapping approaches. Normal adult and …
urothelium and the lamina propria through optical mapping approaches. Normal adult and …
Neurophysiology of the lower urinary tract
JM Beckel, G Holstege - Urinary Tract, 2011 - Springer
The lower urinary tract (LUT) has two functions:(1) the storage of waste products in the form
of urine and (2) the elimination of those wastes through micturition. The LUT operates in a …
of urine and (2) the elimination of those wastes through micturition. The LUT operates in a …
Aberrant reflexes and function of the pelvic organs following spinal cord injury in man
MD Craggs, AV Balasubramaniam, EAL Chung… - Autonomic …, 2006 - Elsevier
Spinal cord injuries can be devastating on quality of life and lost opportunities due to their
impact on bladder, bowel and sexual functions. Supra-sacral spinal lesions can cause …
impact on bladder, bowel and sexual functions. Supra-sacral spinal lesions can cause …