In the normal urinary bladder, tachykinins (TKs) are expressed in a population of bladder
nociceptors that is sensitive to the excitatory and desensitizing effects of capsaicin (ie …

The inability to control timely bladder emptying is one of the most serious challenges among
the many functional deficits that occur after a spinal cord injury. We previously demonstrated …

As current clinical approaches for lower urinary tract (LUT) dysfunction such as
pharmacological and electrical stimulation treatments lack target specificity, thus resulting in …

Neurotrophins (NTs), particularly Nerve Growth Factor (NGF) and Brain-Derived
Neurotrophic Factor (BDNF), have attracted increasing attention in the context of visceral …

Study design: Literature review. Objectives: To present a comprehensive overview of
autonomic assessment in experimental spinal cord injury (SCI). Methods: A systematic …

Spinal cord injury (SCI) triggers profound changes in visceral and somatic targets of sensory
neurons below the level of injury. Despite this, little is known about the influence of injury to …

BACKGROUND AND PURPOSE Diabetic cystopathy is one of the most common and
incapacitating complications of diabetes mellitus. This study aimed to evaluate the …

We examined the modulation of intrinsic (ie, spontaneous) detrusor contractions by the
urothelium and the lamina propria through optical mapping approaches. Normal adult and …

The lower urinary tract (LUT) has two functions:(1) the storage of waste products in the form
of urine and (2) the elimination of those wastes through micturition. The LUT operates in a …

Spinal cord injuries can be devastating on quality of life and lost opportunities due to their
impact on bladder, bowel and sexual functions. Supra-sacral spinal lesions can cause …