Molecular mechanisms and pathophysiological significance of eryptosis

SA Alghareeb, MA Alfhili, S Fatima - International Journal of Molecular …, 2023 - mdpi.com
Despite lacking the central apoptotic machinery, senescent or damaged RBCs can undergo
an unusual apoptosis-like cell death, termed eryptosis. This premature death can be caused …

Lipid nanoparticle technology for delivering biologically active fatty acids and monoglycerides

JYB Tan, BK Yoon, NJ Cho, J Lovrić, M Jug… - International journal of …, 2021 - mdpi.com
There is enormous interest in utilizing biologically active fatty acids and monoglycerides to
treat phospholipid membrane-related medical diseases, especially with the global health …

Endocytosis of red blood cell extracellular vesicles by macrophages leads to cytoplasmic heme release and prevents foam cell formation in atherosclerosis

TT Pham, AH Le, CP Dang, SY Chong… - Journal of …, 2023 - Wiley Online Library
Extracellular vesicles (EVs) can be produced from red blood cells (RBCs) on a large scale
and used to deliver therapeutic payloads efficiently. However, not much is known about the …

Bio-lubricant properties analysis of drilling an innovative design of bioactive kinetic screw into bone

CA Andreucci, EMM Fonseca, RN Jorge - Designs, 2023 - mdpi.com
Biotribology is applied to study the friction, wear, and lubrication of biological systems or
natural phenomena under relative motion in the human body. It is a multidisciplinary field …

Cyclodextrins increase membrane tension and are universal activators of mechanosensitive channels

CD Cox, Y Zhang, Z Zhou, T Walz… - Proceedings of the …, 2021 - National Acad Sciences
The bacterial mechanosensitive channel of small conductance (MscS) has been extensively
studied to understand how mechanical forces are converted into the conformational …

Engineering Synthetic Erythrocytes as Next‐Generation Blood Substitutes

FL Gomes, SH Jeong, SR Shin, J Leijten… - Advanced Functional …, 2024 - Wiley Online Library
Blood scarcity is one of the main causes of healthcare disruptions worldwide, with blood
shortages occurring at an alarming rate. Over the last decades, blood substitutes have …

[HTML][HTML] Using cyclodextrin-induced lipid substitution to study membrane lipid and ordered membrane domain (raft) function in cells

P Suresh, E London - Biochimica et Biophysica Acta (BBA)-Biomembranes, 2022 - Elsevier
Methods for efficient cyclodextrin-induced lipid exchange have been developed in our lab.
These make it possible to almost completely replace the lipids in the outer leaflet of artificial …

Quantitative relationship between cholesterol distribution and ordering of lipids in asymmetric lipid bilayers

M Aghaaminiha, AM Farnoud, S Sharma - Soft Matter, 2021 - pubs.rsc.org
The plasma membrane of eukaryotic cells is known to be compositionally asymmetric.
Certain phospholipids, such as sphingomyelin and phosphatidylcholine species, are …

Bombyx mori Cecropin D could trigger cancer cell apoptosis by interacting with mitochondrial cardiolipin

F Ramos-Martín, C Herrera-León, N d'Amelio - Biochimica et Biophysica …, 2022 - Elsevier
Cecropin D is an antimicrobial peptide from Bombyx mori displaying anticancer and pro-
apoptotic activities and, together with Cecropin XJ and Cecropin A, one of the very few …

Two-pore channels regulate endomembrane tension to enable remodeling and resolution of phagolysosomes

SR Chadwick, D Barreda, JZ Wu… - Proceedings of the …, 2024 - National Acad Sciences
Phagocytes promptly resolve ingested targets to replenish lysosomes and maintain their
responsiveness. The resolution process requires that degradative hydrolases, solute …