The endothelium, a cellular monolayer lining the blood vessel wall, plays a critical role in
maintaining multiorgan health and homeostasis. Endothelial functions in health include …

Genome-wide sequencing has led to the discovery of thousands of long non-coding RNA
(lncRNA) loci in the human genome, but evidence of functional significance has remained …

Atherosclerosis is driven by multifaceted contributions of the immune system within the
circulation and at vascular focal sites. However, specific characteristics of dysregulated …

Although ferroptosis has been recognized as a novel antitumoral treatment, high expression
of nuclear factor erythroid 2-related factor 2 (NRF2) has been reported to be an antioxidant …

Research showing that microRNAs (miRNAs) are versatile regulators of gene expression
has instigated tremendous interest in cardiovascular research. The overwhelming majority of …

The mammalian genome is pervasively transcribed and the functional significance of many
long non-coding RNA (lncRNA) transcripts are gradually being elucidated. Metastasis …

Immune cells in atherosclerosis include T, B, natural killer (NK) and NKT cells,
macrophages, monocytes, dendritic cells (DCs), neutrophils, and mast cells. Advances in …

MicroRNAs (miRNAs) play indispensable roles in posttranscriptional gene regulation. Their
cellular regulatory impact is determined not solely by their sheer number, which likely …

Background Circular RNA (circRNA) has been implicated in various diseases; however, its
role in atopic dermatitis (AD) or psoriasis remains unclear. Objective We sought to determine …

Cardiovascular disease (CVD) has overtaken infectious illnesses as the leading cause of
mortality and disability worldwide. The pathology that underpins CVD is atherosclerosis …