Recent advances in the understanding of antibiotic resistance in Clostridium difficile infection

P Spigaglia - Therapeutic advances in infectious disease, 2016 - journals.sagepub.com
Clostridium difficile epidemiology has changed in recent years, with the emergence of highly
virulent types associated with severe infections, high rates of recurrences and mortality …

Clostridioides difficile infection: history, epidemiology, risk factors, prevention, clinical manifestations, treatment, and future options

S Di Bella, G Sanson, J Monticelli… - Clinical Microbiology …, 2024 - Am Soc Microbiol
Clostridioides difficile infection (CDI) is one of the major issues in nosocomial infections.
This bacterium is constantly evolving and poses complex challenges for clinicians, often …

Clostridium difficile infection: an epidemiology update

AC De Roo, SE Regenbogen - Clinics in colon and rectal …, 2020 - thieme-connect.com
Clostridium (reclassified as “Clostridioides”) difficile infection (CDI) is a healthcare-
associated infection and significant source of potentially preventable morbidity, recurrence …

Antibiotic Resistances of Clostridium difficile

P Spigaglia, P Mastrantonio, F Barbanti - Updates on Clostridium difficile …, 2018 - Springer
The rapid evolution of antibiotic resistance in Clostridium difficile and the consequent effects
on prevention and treatment of C. difficile infections (CDIs) are matter of concern for public …

Clostridium difficile ribotype 017 – characterization, evolution and epidemiology of the dominant strain in Asia

K Imwattana, DR Knight, B Kullin… - Emerging Microbes & …, 2019 - Taylor & Francis
Clostridium difficile ribotype (RT) 017 is an important toxigenic C. difficile RT which, due to a
deletion in the repetitive region of the tcdA gene, only produces functional toxin B. Strains …

Japanese clinical practice guidelines for management of Clostridioides (Clostridium) difficile infection

H Kunishima, H Ohge, H Suzuki, A Nakamura… - Journal of Infection and …, 2022 - jiac-j.com
Toxigenic culture and cytotoxicity assays are standard tests for detecting C. difficile infection
(CDI). Others include immunochromatographic strips, a rapid diagnostic test that detects …

Clostridioides (Clostridium) difficile infection burden in Japan: a multicenter prospective study

H Kato, M Senoh, H Honda, T Fukuda, Y Tagashira… - Anaerobe, 2019 - Elsevier
Clostridioides (Clostridium) difficile is the leading cause of healthcare-associated infectious
diarrhea in the developed world. Retrospective studies have shown a lower incidence of C …

Clostridioides difficile infection in the Asia-Pacific region

DA Collins, KM Sohn, Y Wu, K Ouchi… - Emerging Microbes & …, 2020 - Taylor & Francis
Clostridioides difficile causes healthcare-related diarrhoea in high-income countries. Highly
resistant spores persist in healthcare facilities, primarily infecting patients who have recently …

High prevalence of toxigenic Clostridium difficile in public space lawns in Western Australia

P Moono, SC Lim, TV Riley - Scientific Reports, 2017 - nature.com
Clostridium difficile is a well-established hospital pathogen. Recently, it has been detected
increasingly in patients without hospital contact. Given this rise in community associated …

The Epidemiology of Clostridium difficile Infection in Japan: A Systematic Review

TV Riley, T Kimura - Infectious diseases and therapy, 2018 - Springer
To increase understanding of the epidemiology, risks, consequences and resource
utilization of Clostridium difficile infection (CDI) in Japan, a systematic literature review was …