C-reactive protein (CRP) is a short pentraxin mainly found as a pentamer in the circulation,
or as non-soluble monomers CRP (mCRP) in tissues, exerting different functions. This …

The RAAS through its physiological effectors plays a key role in promoting and maintaining
inflammation. Inflammation is an important mechanism in the development and progression …

The prototypic acute-phase reactant C-reactive protein (CRP) has long been recognized as
a useful marker and gauge of inflammation. CRP also plays an important role in host …

Fibrosis is defined as a fibroproliferative or abnormal fibroblast activation‐related disease.
Deregulation of wound healing leads to hyperactivation of fibroblasts and excessive …

With the discovery of endothelial progenitor cells (EPCs) in the late 1990s, a paradigm shift
in the concept of neoangiogenesis occurred. The identification of circulating EPCs in …

Recent experimental and human studies have shown that hyperuricemia is associated with
hypertension, systemic inflammation, and cardiovascular disease mediated by endothelial …

Endothelial progenitor cells (EPCs) are essential in vasculogenesis and wound healing, but
their circulating and wound level numbers are decreased in diabetes. This study aimed to …

The important role of the vascular endothelium in cardiovascular health is increasingly
recognized. However, mature endothelial cells possess limited regenerative capacity. There …

Cell therapy is a promising option for treating ischemic diseases and heart failure. Adult
stem and progenitor cells from various sources have experimentally been shown to augment …

Trimethylamine N-oxide (TMAO) is a metabolite originated from bacterial metabolism of
choline-rich foods. Evidence suggests an association between TMAO and atherosclerosis …