[HTML][HTML] Peptide-drug conjugates and their targets in advanced cancer therapies

P Hoppenz, S Els-Heindl, AG Beck-Sickinger - Frontiers in chemistry, 2020 - frontiersin.org
Cancer became recently the leading cause of death in industrialized countries. Even though
standard treatments achieve significant effects in growth inhibition and tumor elimination …

[HTML][HTML] Obesity and its comorbidities, current treatment options and future perspectives: Challenging bariatric surgery?

S Kloock, CG Ziegler, U Dischinger - Pharmacology & Therapeutics, 2023 - Elsevier
Obesity and its comorbidities, including type 2 diabetes mellitus, cardiovascular disease,
heart failure and non-alcoholic liver disease are a major health and economic burden with …

[HTML][HTML] Sympathetic nervous system activation and heart failure: Current state of evidence and the pathophysiology in the light of novel biomarkers

JA Borovac, D D'Amario, J Bozic… - World journal of …, 2020 - ncbi.nlm.nih.gov
Heart failure (HF) is a complex clinical syndrome characterized by the activation of at least
several neurohumoral pathways that have a common role in maintaining cardiac output and …

[HTML][HTML] Bisphenol A (BPA) leading to obesity and cardiovascular complications: a compilation of current in vivo study

R Naomi, MD Yazid, H Bahari, YY Keong… - International journal of …, 2022 - mdpi.com
BPA is one of the most common endocrine disruptors that is widely being manufactured
daily nationwide. Although scientific evidence supports claims of negative effects of BPA on …

Cell atlas of the foetal human heart and implications for autoimmune-mediated congenital heart block

H Suryawanshi, R Clancy, P Morozov… - Cardiovascular …, 2020 - academic.oup.com
Aims Investigating human heart development and applying this to deviations resulting in
disease is incomplete without molecular characterization of the cell types required for …

The role of the autonomic nervous system in cardiac arrhythmias: the neuro-cardiac axis, more foe than friend?

AA Manolis, TA Manolis, EJ Apostolopoulos… - Trends in cardiovascular …, 2021 - Elsevier
The autonomic nervous system (ANS) with its two limbs, the sympathetic (SNS) and
parasympathetic nervous system (PSNS), plays a critical role in the modulation of cardiac …

[HTML][HTML] based sensors for rapid important biomarkers detection

B Kuswandi, MA Hidayat, E Noviana - Biosensors and Bioelectronics: X, 2022 - Elsevier
Paper-based sensors have received increasing attention in the last decade, their use has
spread to various application fields, such as clinical diagnostic, food safety, environmental …

Physiological and therapeutic roles of neuropeptide Y on biological functions

P Shende, D Desai - Cell Biology and Translational Medicine, Volume 7 …, 2020 - Springer
Neuropeptide Y (NPY), an amino acid, used for various physiological processes for
management and treatment of various ailments related to central nervous system …

Signaling and function of cardiac autonomic nervous system receptors: Insights from the GPCR signalling universe

A Lymperopoulos, N Cora, J Maning, AR Brill… - The FEBS …, 2021 - Wiley Online Library
The two branches of the autonomic nervous system (ANS), adrenergic and cholinergic, exert
a multitude of effects on the human myocardium thanks to the activation of distinct G protein …

The cardiac sympathetic co-transmitter neuropeptide Y is pro-arrhythmic following ST-elevation myocardial infarction despite beta-blockade

M Kalla, G Hao, N Tapoulal, J Tomek, K Liu… - European heart …, 2020 - academic.oup.com
Aims ST-elevation myocardial infarction is associated with high levels of cardiac sympathetic
drive and release of the co-transmitter neuropeptide Y (NPY). We hypothesized that despite …