Results from recent clinical trials of antibodies that target amyloid-β (Aβ) for Alzheimer's
disease have created excitement and have been heralded as corroboration of the amyloid …

Oxidative stress is proposed as a regulatory element in ageing and various neurological
disorders. The excess of oxidants causes a reduction of antioxidants, which in turn produce …

Cancer and Alzheimer's disease (AD) are characterized by (i) opposing biological
mechanisms,(ii) an inverse correlation between their incidences, and (iii) oxidative stress …

Alzheimer's disease (AD) is a devastating neurodegenerative disorder without a cure. Most
AD cases are sporadic where age represents the greatest risk factor. Lack of understanding …

Neurodegenerative diseases pose a substantial socioeconomic burden on society.
Unfortunately, the aging world population and lack of effective cures foreshadow a negative …

A wide range of neurodegenerative diseases (NDs), including Alzheimer's disease,
Parkinson's disease, Huntington's disease, and prion diseases, share common mechanisms …

Brain iron homeostasis is increasingly recognized as a potential target for the development
of drug therapies for aging‐related disorders. Dysregulation of iron metabolism associated …

Oxidative stress plays a significant role in the pathogenesis of Alzheimer's disease (AD), a
devastating disease of the elderly. The brain is more vulnerable than other organs to …

Copper is an important trace element that is required for essential enzymes. However, due
to its redox activity, copper can also lead to the generation of toxic reactive oxygen species …

Proteinopathy and excessive production of reactive oxygen species (ROS), which are the
principal features observed in the Alzheimer's disease (AD) brain, contribute to neuronal …