The role and mechanism of AMPK in pulmonary hypertension
J Hou, Y Nie, Y Wen, S Hua, Y Hou… - Therapeutic …, 2024 - journals.sagepub.com
Pulmonary hypertension (PH) is a chronic progressive disease with high mortality. There
has been more and more research focusing on the role of AMPK in PH. AMPK consists of …
has been more and more research focusing on the role of AMPK in PH. AMPK consists of …
[HTML][HTML] Exosomal miR-663b from “M1” macrophages promotes pulmonary artery vascular smooth muscle cell dysfunction through inhibiting the AMPK/Sirt1 axis
H Ma, Y Yu, L Mo, Q Chen, H Dong, Y Xu… - Aging (albany …, 2023 - ncbi.nlm.nih.gov
Background: Inflammatory mediators from macrophages are proven to be involved in
pulmonary vascular remodeling in pulmonary hypertension (PH). Here, this study intends to …
pulmonary vascular remodeling in pulmonary hypertension (PH). Here, this study intends to …
[HTML][HTML] The Metabolic Syndrome: An Overview and Proposed Mechanisms
Obesity has emerged as a major public health challenge in the 21st century, contributing to
the rising prevalence of metabolic syndrome (MetS), a cluster of interrelated health risk …
the rising prevalence of metabolic syndrome (MetS), a cluster of interrelated health risk …
A modified Fangji Huangqi decoction ameliorates pulmonary artery hypertension via phosphatidylinositide 3-kinases/protein kinase B-mediated regulation of …
Z Xue, M Zhou, Y Liu, H Qin, Y Li, Y Zhu… - Journal of …, 2023 - Elsevier
Ethnopharmacological relevance Pulmonary artery hypertension (PAH) is a progressive and
fatal lung disease of multifactorial etiology, which arouses an enhanced interest in PAH …
fatal lung disease of multifactorial etiology, which arouses an enhanced interest in PAH …
Resveratrol attenuates cyclosporin A-induced upregulation of the thromboxane A2 receptor and hypertension via the AMPK/SIRT1 and MAPK/NF-κB pathways in the …
Q Li, H Cao, X Xu, Y Chen, Y Zhang, Y Mi, X Zhu… - European Journal of …, 2024 - Elsevier
Cyclosporin A, an immunosuppressive agent, is extensively utilized for the prevention of
transplant rejection and treat autoimmune disease in the clinic, despite its association with a …
transplant rejection and treat autoimmune disease in the clinic, despite its association with a …
SubSol-HIe is an AMPK-dependent hypoxia-responsive subnucleus of the nucleus tractus solitarius that coordinates the hypoxic ventilatory response and protects …
S MacMillan, DP Burns, KD O'Halloran… - Pflügers Archiv-European …, 2024 - Springer
Functional magnetic resonance imaging (fMRI) suggests that the hypoxic ventilatory
response is facilitated by the AMP-activated protein kinase (AMPK), not at the carotid bodies …
response is facilitated by the AMP-activated protein kinase (AMPK), not at the carotid bodies …
Omentin-1 ameliorates pulmonary arterial hypertension by inhibiting endoplasmic reticulum stress through AMPKα signaling
X Deng, H Luo, J He, W Deng… - Clinical and Experimental …, 2024 - Taylor & Francis
Background Endothelial dysfunction of the pulmonary artery contributes to hypoxia-induced
pulmonary arterial hypertension (PAH). Omentin-1, as a novel adipocytokine, plays an …
pulmonary arterial hypertension (PAH). Omentin-1, as a novel adipocytokine, plays an …
An AMPK-dependent hypoxia-responsive subnucleus of the nucleus tractus solitarius coordinates the hypoxic ventilatory response and protects against apneoa in …
S MacMillan, DP Burns, KD O'Halloran, AM Evans - 2023 - researchsquare.com
Functional magnetic resonance imaging (fMRI) suggests that the hypoxic ventilatory
response is facilitated by the AMP-activated protein kinase (AMPK), not at the carotid bodies …
response is facilitated by the AMP-activated protein kinase (AMPK), not at the carotid bodies …