[HTML][HTML] Magnesium isoglycyrrhizinate ameliorates high fructose-induced liver fibrosis in rat by increasing miR-375-3p to suppress JAK2/STAT3 pathway and TGF-β1 …

Y Yang, X Zhao, H Xu, S Wang, Y Pan… - Acta Pharmacologica …, 2019 - nature.com
Increasing evidence has demonstrated that excessive fructose intake induces liver fibrosis.
Epithelial–mesenchymal transition (EMT) driven by transforming growth factor-β1 (TGF …

The regulation of CIN-like TCP transcription factors

J Lan, G Qin - International journal of molecular sciences, 2020 - mdpi.com
TEOSINTE BRANCHED1/CYCLOIDEA/PROLIFERATING CELL FACTOR 1 and 2 (TCP)
family proteins are the plant-specific transcription factors extensively participating in diverse …

The burden of hepatocellular carcinoma in non-alcoholic fatty liver disease: screening issue and future perspectives

G Pennisi, C Celsa, A Giammanco, F Spatola… - International journal of …, 2019 - mdpi.com
In recent decades, non-alcoholic fatty liver disease (NAFLD) has become the most common
liver disease in the Western world, and the occurrence of its complications, such as …

Advances in noninvasive biomarkers for nonalcoholic fatty liver disease

GE Gîlcă-Blanariu, DS Budur, DE Mitrică, E Gologan… - Metabolites, 2023 - mdpi.com
Nonalcoholic fatty liver disease (NAFLD) currently represents one of the most common liver
diseases worldwide. Early diagnosis and disease staging is crucial, since it is mainly …

Plasma microRNA levels are associated with hepatitis B e antigen status and treatment response in chronic hepatitis B patients

MH Van Der Ree, L Jansen, Z Kruize… - The Journal of …, 2017 - academic.oup.com
Abstract Background. Hepatitis B virus (HBV) modulates microRNA (miRNA) expression to
support viral replication. The aim of this study was to identify miRNAs associated with …

[HTML][HTML] RISC assembly and post-transcriptional gene regulation in Hepatocellular Carcinoma

PK Santhekadur, DP Kumar - Genes & diseases, 2020 - Elsevier
RNA-induced silencing complex (RISC) is one of the basic eukaryotic cellular machinery
which plays a pivotal role in post-transcriptional gene regulation. Discovery of miRNAs and …

Cell-free circulating nucleic acids as early biomarkers for NAFLD and NAFLD-associated disorders

A Turchinovich, A Baranova, O Drapkina… - Frontiers in …, 2018 - frontiersin.org
Non-alcoholic fatty liver disease (NAFLD) is the worldwide most common cause of chronic
liver pathology, which prevalence strongly correlates with the increasing incidence of …

Heart failure with preserved ejection fraction and non‐alcoholic fatty liver disease: new insights from bioinformatics

A Wang, Z Li, Z Sun, Y Wang, S Fu, D Zhang… - ESC heart …, 2023 - Wiley Online Library
Aims Heart failure with preserved ejection fraction (HFpEF) and non‐alcoholic fatty liver
disease (NAFLD) are related conditions with an increasing incidence. The mechanism of …

Targeting miRNA by natural products: A novel therapeutic approach for nonalcoholic fatty liver

M Zobeiri, F Parvizi, MR Kalhori… - Evidence‐Based …, 2021 - Wiley Online Library
The increasing prevalence of nonalcoholic fatty liver disease (NAFLD) as multifactorial
chronic liver disease and the lack of a specific treatment have begun a new era in its …

Comprehensive evaluation of extracellular small RNA isolation methods from serum in high throughput sequencing

Y Guo, K Vickers, Y Xiong, S Zhao, Q Sheng, P Zhang… - BMC genomics, 2017 - Springer
Background DNA and RNA fractions from whole blood, serum and plasma are increasingly
popular analytes that are currently under investigation for their utility in the diagnosis and …