High-fructose drinks affect microRNAs expression differently in lean and obese mice

B Hanousková, B Neprašová, L Skálová… - The Journal of …, 2019 - Elsevier
High fructose intake from soft drinks and sweets is assumed to have a negative impact on
human health. Yet in spite of intensive research, the molecular mechanisms of these effects …

[HTML][HTML] Roles of microRNA in liver cancer

J Tao, L Jiang, X Chen - Liver Research, 2018 - Elsevier
Primary liver cancer is the fifth most common cancer and the third leading cause of cancer
death worldwide. MicroRNAs (miRNAs) are small non-coding RNA molecules that …

Saturated Fatty Acids Promote Hepatocytic Senecence through Regulation of miR‐34a/Cyclin‐Dependent Kinase 6

Y Qin, L Duan, Y He, C Yuan, T Wang… - Molecular Nutrition & …, 2020 - Wiley Online Library
Scope Obesity increases intracellular lipid accumulation in hepatocytes, which can induce
non‐alcoholic fatty liver disease (NAFLD). With progression of NAFLD, a sizable fraction of …

The role of epigenomic alterations in furan-induced hepatobiliary pathologies

A de Conti, FA Beland, IP Pogribny - Food and Chemical Toxicology, 2017 - Elsevier
Furan, a volatile heterocyclic organic chemical found in a wide spectrum of common human
foods, is a liver toxicant and carcinogen in mice and rats. The carcinogenic effects of furan …

Therapeutic role of Artemether in the prevention of hepatic steatosis through miR‐34a‐5p/PPARα pathway

L Chen, S Yu, S Hong, X Lin, X Zhu… - Drug Development …, 2023 - Wiley Online Library
Artemether (ATM) is a natural antimalarial drug that can also regulate glucose and lipid
metabolism. However, little is known regarding its pharmacological action in metabolic …

MicroRNA-31 reflects IL-6 expression in cancer tissue and is related with poor prognosis in bile duct cancer

K Ishigami, K Nosho, H Koide, S Kanno… - …, 2018 - academic.oup.com
Bile duct cancer is a highly aggressive malignancy wherein early diagnosis is difficult and
few treatment options are available. MicroRNA-31 (miR-31) is reported to be related with …

The implications of noncoding rnas in the evolution and progression of nonalcoholic fatty liver disease (Nafld)-related hcc

I Rusu, R Pirlog, P Chiroi, A Nutu, VR Puia… - International Journal of …, 2022 - mdpi.com
Nonalcoholic fatty liver disease (NAFLD) is the most prevalent liver pathology worldwide.
Meanwhile, liver cancer represents the sixth most common malignancy, with hepatocellular …

Nonalcoholic fatty liver disease versus alcohol-related liver disease: is it really so different?

A Craciun, C Lackner… - Current pharmaceutical …, 2020 - ingentaconnect.com
Nonalcoholic fatty liver disease and alcohol-related liver disease together, compose the
majority of cases of liver disease and cirrhosis worldwide. Although in the last years, there …

Moringa oleifera L. mediated zinc oxide nano-biofertilizer alleviates non-alcoholic steatohepatitis via modulating de novo lipogenesis pathway and miRNA-122 …

DM Mohammed, MB Salem, M Elzallat, OA Hammam… - Food Bioscience, 2024 - Elsevier
Nano-biofertilizer has recently been shown to alter plant growth through a variety of
physiological and morphological changes which many improves the quality of plant and …

Plasma EBV microRNAs in paediatric renal transplant recipients

J Hassan, J Dean, CF De Gascun, M Riordan… - Journal of …, 2018 - Springer
Abstract Background Epstein–Barr virus (EBV) was the first human virus identified to express
microRNA (miRNA). To date, 44 mature miRNAs are encoded for within the EBV genome …