[HTML][HTML] Unraveling the Significance of EPH/Ephrin Signaling in Liver Cancer: Insights into Tumor Progression and Therapeutic Implications

SP Papadakos, IE Stergiou, N Gkolemi, K Arvanitakis… - Cancers, 2023 - mdpi.com
Simple Summary This narrative literature review delves into the role of EPH/ephrin signaling
in liver cancer and its implications for tumor progression and potential therapeutic strategies …

[HTML][HTML] Meeting at the crossroad between obesity and hepatic carcinogenesis: unique pathophysiological pathways raise expectations for innovative therapeutic …

K Arvanitakis, SP Papadakos, V Lekakis… - International Journal of …, 2023 - mdpi.com
The escalating global prevalence of obesity and its intricate association with the
development of hepatocellular carcinoma (HCC) pose a substantial challenge to public …

[HTML][HTML] RNA 5-methylcytosine writer NSUN5 promotes hepatocellular carcinoma cell proliferation via a ZBED3-dependent mechanism

X Gu, P Li, X Gao, Y Ru, C Xue, S Zhang, Y Liu, X Hu - Oncogene, 2024 - nature.com
Hepatocellular carcinoma (HCC) is one of the leading contributors to cancer-related
mortality worldwide. Nop2/Sun domain family member 5 (NSUN5), a conserved RNA 5 …

[HTML][HTML] Pharmacological therapy of metabolic dysfunction-associated steatotic liver disease-driven hepatocellular carcinoma

Y Wang, JS Fleishman, T Li, Y Li, Z Ren… - Frontiers in …, 2024 - frontiersin.org
In light of a global rise in the number of patients with type 2 diabetes mellitus (T2DM) and
obesity, non-alcoholic fatty liver disease (NAFLD), now known as metabolic dysfunction …

[HTML][HTML] Mitochondrial Dysfunction in Metabolic Dysfunction Fatty Liver Disease (MAFLD)

Y Zhao, Y Zhou, D Wang, Z Huang, X Xiao… - International Journal of …, 2023 - mdpi.com
Nonalcoholic fatty liver disease (NAFLD) has become an increasingly common disease in
Western countries and has become the major cause of liver cirrhosis or hepatocellular …

[HTML][HTML] Tumor necrosis factor-alpha and adiponectin in nonalcoholic fatty liver disease-associated hepatocellular carcinoma

ID Vachliotis, I Valsamidis, SA Polyzos - Cancers, 2023 - mdpi.com
Simple Summary The prevalence of nonalcoholic fatty liver disease (NAFLD)-associated
hepatocellular carcinoma (HCC) is rapidly increasing, following the growing prevalence of …

Emerging mRNA Technology for Liver Disease Therapy

J Wang, Y Fang, Z Luo, J Wang, Y Zhao - ACS nano, 2024 - ACS Publications
Liver diseases have consistently posed substantial challenges to global health. It is crucial
to find innovative methods to effectively prevent and treat these diseases. In recent times …

Noncoding RNAs and programmed cell death in hepatocellular carcinoma: Significant role of epigenetic modifications in prognosis, chemoresistance, and tumor …

R Arefnezhad, S Ashna… - Cell Biology …, 2024 - Wiley Online Library
Hepatocellular carcinoma (HCC) is the most common type of liver cancer with a high death
rate in the world. The molecular mechanisms related to the pathogenesis of HCC have not …

[HTML][HTML] The association between endocrine disrupting chemicals and nonalcoholic fatty liver disease: A systematic review and meta-analysis

K Pan, J Xu, Y Xu, C Wang, J Yu - Pharmacological Research, 2024 - Elsevier
Nonalcoholic fatty liver disease (NAFLD) is one of the leading causes of chronic liver
disease worldwide. Epidemiological studies have reported that exposure of the population …

[HTML][HTML] Enhancing HepG2 cell apoptosis with a combined nanoparticle delivery of miR-128-3p agomir and Oroxin B: A novel drug delivery approach based on PI3K …

H Wang, X Shen, X Zhu, S Zeng, S Cai - Asian Journal of Pharmaceutical …, 2024 - Elsevier
Hepatocellular carcinoma (HCC) shows the highest morbidity among liver cancers and
accounts for a major factor inducing cancer-associated mortality globally. It is characterized …