Covering: up to August 2001This review covers the structure and function of heparin and
heparan sulfate glycosaminoglycans. Their chemical structures are discussed, including …

Different chromatographic and electrophoretic techniques commonly used in the
instrumental inspection of herbal medicines (HM) are first comprehensively reviewed …

Publisher Summary This chapter discusses the structural aspects and structure–activity
relationships of heparin/heparan sulfate (HS). The molecular mechanism behind the …

Glycosarninoglycans (GAGs) play an intricate role in the extracellular matrix (ECM), not only
as soluble components and polyelectrolytes, but also by specific interactions with growth …

RJ Linhardt,**'* JE Turnbull, § HM Wang,* D. Loganathan,* and JT Gallagher11 Division of
Medicinal and Natural Products Chemistry, College of Pharmacy, University of Iowa, Iowa …

Heparin lyase I has been purified from Flavobacterium heparinum and has been partially
characterized (Yang, VC, Linhardt, RJ, Berstein, H., Cooney, CL, and Langer, R.(1985) J …

This volume is the first book to give a complete description of the techniques, materials, and
instrumentation of column HPLC and its application to essentially all primary and secondary …

As part of our continuing studies on heparin, the present paper uses 13C-nmr spectroscopy
to examine the acidity of heparin's uronic acid carboxylate groups. Heparin contains three …

Revised Manuscript Received May 4, 1993 abstract: An understanding of the substrate
specificity study of the heparin lyases (heparinase and heparitinases) is crucial for …

Revised Manuscript Received February 9, 1993 abstract: The binding of human acidic
fibroblast growth factor (aFGF) to heparin has been analyzed by a variety of different …