Molecular mechanisms of ROS production and oxidative stress in diabetes

P Newsholme, VF Cruzat, KN Keane… - Biochemical …, 2016 - portlandpress.com
Oxidative stress and chronic inflammation are known to be associated with the development
of metabolic diseases, including diabetes. Oxidative stress, an imbalance between oxidative …

The noncanonical pathway for in vivo nitric oxide generation: the nitrate-nitrite-nitric oxide pathway

V Kapil, RS Khambata, DA Jones, K Rathod… - Pharmacological …, 2020 - ASPET
In contrast to nitric oxide, which has well established and important roles in the regulation of
blood flow and thrombosis, neurotransmission, the normal functioning of the genitourinary …

Dietary nitrate and physical performance

AM Jones, C Thompson, LJ Wylie… - Annual review of …, 2018 - annualreviews.org
Nitric oxide (NO) plays a plethora of important roles in the human body. Insufficient
production of NO (for example, during older age and in various disease conditions) can …

Dietary nitrate supplementation and exercise performance

AM Jones - Sports medicine, 2014 - Springer
Dietary nitrate is growing in popularity as a sports nutrition supplement. This article reviews
the evidence base for the potential of inorganic nitrate to enhance sports and exercise …

Neuronal nitric oxide synthase: structure, subcellular localization, regulation, and clinical implications

L Zhou, DY Zhu - Nitric oxide, 2009 - Elsevier
Nitric oxide (NO), a free gaseous signaling molecule, is involved in the regulation of the
cardiovascular, nervous and immune system. The neurotransmitter function of nitric oxide is …

Dietary nitrate and nitric oxide metabolism mouth, circulation, skeletal muscle, and exercise performance

AM Jones, A Vanhatalo, DR Seals, MJ Rossman… - 2020 - nih.brage.unit.no
Nitric oxide (NO) is a gaseous signaling molecule that plays an important role in myriad
physiological processes including the regulation of vascular tone, neurotransmission …

Influence of acute dietary nitrate supplementation on 50 mile time trial performance in well-trained cyclists

DP Wilkerson, GM Hayward, SJ Bailey… - European journal of …, 2012 - Springer
Dietary nitrate supplementation has been reported to improve short distance time trial (TT)
performance by 1–3% in club-level cyclists. It is not known if these ergogenic effects persist …

No improvement in endurance performance after a single dose of beetroot juice

NM Cermak, R Stinkens… - … journal of sport …, 2012 - journals.humankinetics.com
Introduction: Dietary nitrate supplementation has received much attention in the literature
due to its proposed ergogenic properties. Recently, the ingestion of a single bolus of nitrate …

The muscle fiber type–fiber size paradox: hypertrophy or oxidative metabolism?

T Van Wessel, A De Haan, WJ Van Der Laarse… - European journal of …, 2010 - Springer
An inverse relationship exists between striated muscle fiber size and its oxidative capacity.
This relationship implies that muscle fibers, which are triggered to simultaneously increase …

[HTML][HTML] Factors that moderate the effect of nitrate ingestion on exercise performance in adults: a systematic review with meta-analyses and meta-regressions

KVC Silva, BD Costa, AC Gomes, B Saunders… - Advances in …, 2022 - Elsevier
To identify how variables such as exercise condition, supplementation strategy, participant
characteristics and demographics, and practices that control oral microbiota diversity could …