Organokines in rheumatoid arthritis: A critical review

LF Laurindo, MC de Maio, SM Barbalho… - International Journal of …, 2022 - mdpi.com
Rheumatoid arthritis (RA) is a systemic autoimmune disease that primarily affects the joints.
Organokines can produce beneficial or harmful effects in this condition. Among RA patients …

Natural protein bioinspired materials for regeneration of hard tissues

X Xu, X Chen, J Li - Journal of Materials Chemistry B, 2020 - pubs.rsc.org
The regenerative materials for hard tissues, ie tooth (enamel, dentin, and cementum) and
bone, require extremely high standards in terms of their mechanical properties …

Bone metabolism and RANKL/OPG ratio in rheumatoid arthritis women treated with TNF-α inhibitors

A Jura-Półtorak, A Szeremeta, K Olczyk… - Journal of clinical …, 2021 - mdpi.com
The aim of this study was to evaluate the effect of anti-tumor necrosis factor α (anti-TNF-α)
therapy in combination with methotrexate on bone remodeling and osteoclastogenesis in …

[HTML][HTML] The role of osteoprotegerin (OPG) in fibrosis: its potential as a biomarker and/or biological target for the treatment of fibrotic diseases

H Habibie, A Adhyatmika, D Schaafsma… - Pharmacology & …, 2021 - Elsevier
Fibrosis is defined by excessive formation and accumulation of extracellular matrix proteins,
produced by myofibroblasts, that supersedes normal wound healing responses to injury and …

Osteopontin controls immunosuppression in the tumor microenvironment

MR Shurin - The Journal of clinical investigation, 2018 - Am Soc Clin Investig
Cancer cells evade the immune system through a variety of different mechanisms, including
the inhibition of antitumor effector T cells via checkpoint ligand–receptor interaction …

Identification of anti-citrullinated osteopontin antibodies and increased inflammatory response by enhancement of osteopontin binding to fibroblast-like synoviocytes in …

A Umemoto, T Kuwada, K Murata, M Shiokawa… - Arthritis Research & …, 2023 - Springer
Background Anti-citrullinated protein/peptide antibodies (ACPAs) are present in patients at
onset and have important pathogenic roles during the course of rheumatoid arthritis (RA) …

Interleukin-17 Gene Polymorphism (Rs2275913 G/A, Rs763780 C/T) in Rheumatoid arthritis: Meta-analysis Based on Ethnicity

M Shao, W Xu, H Yang, Y Chen, X Gao… - Immunological …, 2021 - Taylor & Francis
Introduction The association between interleukin (IL)-17A and IL-17 F gene polymorphism
with rheumatoid arthritis (RA) were inconsistent among previous studies. This meta-analysis …

Serum Levels of OPG, RANKL, and RANKL/OPG Ratio in Patients with Ankylosing Spondylitis: A Systematic Review and Meta-analysis

M Chen, X Hu, M Wu, J Yang, R Han, Y Ma… - Immunological …, 2019 - Taylor & Francis
Objectives: To investigate the role of osteoprotegerin (OPG), receptor activator of nuclear
factor-kB ligand (RANKL), and RANKL/OPG ratio in the pathogenesis of ankylosing …

Carbon/Inorganic Hybrid Nanoarchitectures as Carriers for Signaling Elements in Electrochemical Immunosensors: First Biosensor for the Determination of the …

A Valverde, V Serafín, A Montero‐Calle… - …, 2020 - Wiley Online Library
This work reports the development of the first integrated electrochemical immunosensor for
the determination of the ligand receptor activator nuclear factor‐κB (RANKL), a biomarker …

Role of osteopontin as a potential biomarker of pulmonary arterial hypertension in patients with systemic sclerosis and other connective tissue diseases (CTDs)

M Bellan, C Piccinino, S Tonello, R Minisini… - Pharmaceuticals, 2021 - mdpi.com
Pulmonary arterial hypertension (PAH) is a severe complication of connective tissue
diseases (CTD). Its early diagnosis is essential to start effective treatment. In the present …