Bioluminescence is the fascinating natural phenomenon by which living creatures produce
light. Bioluminescence occurs when the oxidation of a small-molecule luciferin is catalysed …

Bioluminescence is a phenomenon that has fascinated mankind for centuries. Today the
phenomenon and its sibling, chemiluminescence, have impacted society with a number of …

Bioluminescence imaging has been widely used in life sciences and biomedical
applications. However, conventional bioluminescence imaging usually operates in the …

Bioluminescence is a natural light source based on luciferase catalysis of its substrate
luciferin. We performed directed evolution on firefly luciferase using a red-shifted and highly …

Lipid nanoparticles (LNPs) represent the most clinically advanced nonviral mRNA delivery
vehicles; however, the full potential of the LNP platform is greatly hampered by inadequate …

Optical imaging has played a pivotal role in deciphering in vivo bioinformatics but is limited
by shallow penetration depth and poor imaging performance owing to interfering tissue …

This book, written by a distinguished scientist in the field, provides a comprehensive
overview of the biochemical aspects of all luminous organisms currently known. It is the first …

Although fluorescent reporters and biosensors have become indispensable tools in
biological and biomedical fields, fluorescence measurements require external excitation …

External light sources, such as lasers, light emitting diodes (LEDs) and lamps, are widely
applied in photodynamic therapy (PDT); however, their use is severely limited by the nature …

Bioluminescence has long been used to image biological processes in vivo. This technology
features luciferase enzymes and luciferin small molecules that produce visible light …