Early predictors of perinatal brain damage: the role of neurobiomarkers

I Bersani, F Pluchinotta, A Dotta, I Savarese… - Clinical Chemistry and …, 2020 - degruyter.com
The early detection of perinatal brain damage in preterm and term newborns (ie
intraventricular hemorrhage, periventricular leukomalacia and perinatal asphyxia) still …

The impact of perinatal inflammation on the electroencephalogram in preterm infants: a systematic review

A Giraud, CM Stephens, GB Boylan, BH Walsh - Pediatric Research, 2022 - nature.com
Background To summarise the association between perinatal inflammation (PI) exposure
and electroencephalography (EEG) features in preterm infants. Methods This systematic …

SIRT1-regulated HMGB1 release is partially involved in TLR4 signal transduction: a possible anti-neuroinflammatory mechanism of resveratrol in neonatal hypoxic …

K Le, EC Daliv, S Wu, F Qian, AI Ali, D Yu… - International …, 2019 - Elsevier
Neonatal hypoxic-ischemic brain injury (HIBI) is a knotty disease that lacks appropriate
treatment. Inflammation is an important contributor to brain damage, and microglia are …

High-mobility group box-1 translocation and release after hypoxic ischemic brain injury in neonatal rats

X Chen, J Zhang, B Kim, S Jaitpal, SS Meng… - Experimental …, 2019 - Elsevier
Inflammation contributes to neonatal brain injury. Pro-inflammatory cytokines represent key
inflammatory meditators in neonatal hypoxic-ischemic (HI) brain injury. The high mobility …

Quantitative estimation of TNF-α and IL-3 by using ELISA from human lung tissue in fatal asphyxial deaths

R Panwar, RS Shekhawat, KK Shukla, M Rao… - Journal of Forensic and …, 2023 - Elsevier
Asphyxia-related deaths have always been a challenging task in the specialty of forensic
pathology. Apart from helpful macroscopical signs (eg, strangulation marks, cyanosis …

Two useful umbilical biomarkers for therapeutic hypothermia decision in patients with hypoxic ischemic encephalopathy with perinatal asphyxia: netrin-1 and neuron …

U Cakir, B Ceran, C Tayman - Fetal and Pediatric Pathology, 2022 - Taylor & Francis
Objective: Hypoxic-ischemic encephalopathy (HIE) has a high risk of mortality in addition to
serious neurological damage. In this study, we investigated the values of umbilical cord …

The performance of the alarmin HMGB1 in pediatric diseases: From lab to clinic

B Li, X Peng, H Li, F Chen, Y Chen… - Immunity …, 2021 - Wiley Online Library
Introduction The ubiquitously expressed nonhistone nuclear protein high‐mobility group box
protein 1 (HMGB1) has different functions related to posttranslational modifications and …

Enrofloxacin hydrochloride toxicological effects on crucian carp reflected by serological changes and neurotoxicity

G Wan, J Huang, R Wang, H Liu, L Wei, X Liang… - … and Physiology Part C …, 2023 - Elsevier
Due to its water solubility and wide applicability, enrofloxacin hydrochloride (EH) may enter
aquatic ecosystems and cause negative effects on aquatic organisms. This study aimed to …

[PDF][PDF] 香草醛对新生大鼠缺氧缺血性脑损伤的神经保护作用研究

汤丽萍, 闫瑾, 范芳, 王浩, 任丽芬 - 现代生物医学进展, 2021 - biomed.cnjournals.com
摘要目的: 探讨香草醛对新生大鼠缺氧缺血性脑损伤(HIBI) 的神经保护作用及机制. 方法:
参考Rice-Vannucci 方法建立HIBI 大鼠模型. HIBI 大鼠建模后立即腹腔注射20 mg/kg (HIBI+ …

Biomarkers in neonatal brain injury: interpreting research into clinical practice

N Efstathiou - Biomarkers in Trauma, Injury and Critical Care, 2023 - Springer
This chapter synopsizes all clinically relevant information found in the literature regarding
brain injury in preterm and full-term neonates for the two most studied biomarkers, S100B …