Multiple sclerosis (MS) is an inflammatory disorder of the central nervous system where
evidence implicates an aberrant adaptive immune response in the accrual of neurological …

In 1997, the first consensus guidelines for haematopoietic SCT (HSCT) in autoimmune
diseases (ADs) were published, while an international coordinated clinical programme was …

Abstract Since Morton and Siegel's epochal experiments 30 years ago animal models have
been successfully utilized both for transfer and resolution of autoimmune diseases (AID) …

NEW-the leading book in its field now fully updated andrevised! Click here to access two
FREE sample chapters! An Essential resource for all hematologists, oncologists …

BACKGROUND AND OBJECTIVE: Although biphenotypic leukemia is now a defined entity,
outcome of this rare form of acute leukemia has not been well documented. We present the …

Multiple sclerosis, systemic lupus erythematosus, and rheumatoid arthritis are immune-
mediated diseases that are responsive to suppression or modulation of the immune system …

Background: Over recent years numerous patients with severe forms of multiple sclerosis
(MS) refractory to conventional therapies have been treated with intense …

Background: Immunoablative high-dose cyclophosphamide without stem-cell rescue
induces durable, complete remission in most patients with aplastic anemia. Objective: To …

A 46 year woman with severe long-lasting SLE received an autologous bone marrow
transplantation utilising CD34+ haematopoietic progenitors following a 3 log T-lymphocyte …

Based on the good results of experimental transplantation in animal models of multiple
sclerosis and of other autoimmune diseases, we have treated 24 patients suffering from …