[HTML][HTML] Lipid rafts as signaling hubs in cancer cell survival/death and invasion: implications in tumor progression and therapy: thematic review series: biology of lipid …
F Mollinedo, C Gajate - Journal of lipid research, 2020 - ASBMB
Cholesterol/sphingolipid-rich membrane domains, known as lipid rafts or membrane rafts,
play a critical role in the compartmentalization of signaling pathways. Physical segregation …
play a critical role in the compartmentalization of signaling pathways. Physical segregation …
The lipid basis of cell death and autophagy
Triglycerides, phospholipids, and cholesterol are prominent lipid types that serve diverse
biological functions. These lipids act as vital structural components of cell membranes …
biological functions. These lipids act as vital structural components of cell membranes …
[HTML][HTML] Plasmalogens, platelet-activating factor and beyond–Ether lipids in signaling and neurodegeneration
F Dorninger, S Forss-Petter, I Wimmer, J Berger - Neurobiology of disease, 2020 - Elsevier
Glycerol-based ether lipids including ether phospholipids form a specialized branch of lipids
that in mammals require peroxisomes for their biosynthesis. They are major components of …
that in mammals require peroxisomes for their biosynthesis. They are major components of …
[HTML][HTML] Bioactive ether lipids: Primordial modulators of cellular signaling
N Rangholia, TM Leisner, SP Holly - Metabolites, 2021 - mdpi.com
The primacy of lipids as essential components of cellular membranes is conserved across
taxonomic domains. In addition to this crucial role as a semi-permeable barrier, lipids are …
taxonomic domains. In addition to this crucial role as a semi-permeable barrier, lipids are …
[HTML][HTML] Antitumor activity of alkylphospholipid edelfosine in prostate cancer models and endoplasmic reticulum targeting
ELH Dakir, C Gajate, F Mollinedo - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Prostate cancer is the second most frequent cancer and the fifth leading cause of cancer
death among men worldwide. While the five-year survival in local and regional prostate …
death among men worldwide. While the five-year survival in local and regional prostate …
Lipid metabolism and Calcium signaling in epithelial ovarian cancer
S Kouba, L Ouldamer, C Garcia, D Fontaine… - Cell calcium, 2019 - Elsevier
Epithelial Ovarian cancer (EOC) is the deadliest gynecologic malignancy and represents the
fifth leading cause of all cancer-related deaths in women. The majority of patients are …
fifth leading cause of all cancer-related deaths in women. The majority of patients are …
[HTML][HTML] Unusual Ether Lipids and Branched Chain Fatty Acids in Sea Cucumber (Cucumaria frondosa) Viscera and Their Seasonal Variation
R Abuzaytoun, SM Budge, W Xia, S MacKinnon - Marine Drugs, 2022 - mdpi.com
The sea cucumber, Cucumaria frondosa, is harvested primarily for its muscular bands and
body wall. Development of a nutraceutical product based on lipid recovered from its viscera …
body wall. Development of a nutraceutical product based on lipid recovered from its viscera …
[HTML][HTML] Mechanisms of induction of tumors by cholesterol and potential therapeutic prospects
Y Xi, Z Yani, M Jing, W Yinhang, H Xiaohui… - Biomedicine & …, 2021 - Elsevier
Increasing evidence suggested that cholesterol is an important integrant of cell membranes,
that plays a key role in tumor progression, immune dysregulation, and pathological changes …
that plays a key role in tumor progression, immune dysregulation, and pathological changes …
[HTML][HTML] CRAC and SK channels: their molecular mechanisms associated with cancer cell development
A Tiffner, V Hopl, I Derler - Cancers, 2022 - mdpi.com
Simple Summary Cell fate is ultimately determined by the precisely coordinated action of the
Ca2+-signaling machinery. During carcinogenesis, Ca2+ signaling is significantly …
Ca2+-signaling machinery. During carcinogenesis, Ca2+ signaling is significantly …
[HTML][HTML] Plasma lipid profile reveals plasmalogens as potential biomarkers for colon cancer screening
AMAP Fernandes, MCF Messias, GHB Duarte… - Metabolites, 2020 - mdpi.com
In this era of precision medicine, there is an increasingly urgent need for highly sensitive
tests for detecting tumors such as colon cancer (CC), a silent disease where the first …
tests for detecting tumors such as colon cancer (CC), a silent disease where the first …