不同病理因素诱导的大鼠心肌肥大模型心肌表型特征及表达谱 Page 1 2023年5月 第31卷第5期 中国
实验动物学报 ACTA LABORATORIUM ANIMALIS SCIENTIA SINICA May 2023 Vol. 31 No. 5 丁月 …

During autophagy, cytosolic cargo is sequestered into double-membrane vesicles called
autophagosomes. The origin and identity of the membranes that form the autophagosome …

The use of statins is necessary for the prevention and treatment of atherosclerosis, and the
criteria for assessing their hypolipidemic effect are clearly defined. Atorvastatin is one of the …

近来研究发现, 作为降脂药物的阿托伐他汀具有神经保护作用, 但具体机制不明.
课题组以往研究结果也发现, 脊髓损伤后细胞的自噬活动被激活, 有利于神经功能的恢复 …

Gliomas are common primary intra-cerebral tumors in adults, and seriously threaten the
health and life of affected patients, especially highly-malignant gliomas, such as …

Macroautophagy (hereafter autophagy) is an intracellular degradative pathway in budding
yeast cells. Certain lipid types play essential roles in autophagy; yet the precise mechanisms …

Rapamycin was shown to reduce infarct size in a non-reperfusion and a slow reperfusion
model of murine stroke; it also improved neurological score and survival in the slow …

Insufficient autophagy has been proposed as a mechanism of cellular aging, as this leads to
the accumulation of dysfunctional macromolecules and organelles. Premature vascular …

The mevalonate pathway (also known as the cholesterol biosynthesis pathway) plays a
crucial metabolic role in normal cell function as well as in the pathological environment. It …