Virus-like particles (VLPs) have become key tools in biology, medicine and even
engineering. After their initial use to resolve viral structures at the atomic level, VLPs were …

Persistent human papillomavirus (HPV) infection is recognized as the main cause of cervical
cancer and other malignant cancers. Although early detection and treatment can be …

Immunization is the most successful method in preventing and controlling infectious
diseases, which has helped saving millions of lives worldwide. The discovery of the human …

Virus-like particles (VLPs) are self-assembled viral protein complexes that mimic the native
virus structure without being infectious. VLPs, similarly to wild type viruses, are able to …

Immuno-oncology has revolutionized cancer treatment and has opened up new
opportunities for developing vaccination methods. DNA-based cancer vaccines have …

HPV-related diseases represent a major cause of morbidity and mortality, although effective
HPV vaccines are available, potentially allowing for the elimination of these malignancies …

Licensed L1-VLP-based immunizations against high-risk mucosal human papillomavirus
(HPV) types have been a great success in reducing anogenital cancers, although they are …

Nanotechnology has emerged as a transformative pathway in vaccine research and
delivery. Nanovaccines, encompassing lipid and nonlipid formulations, exhibit considerable …

Vaccines not requiring cold-chain storage/distribution and suitable for needle-free delivery
are urgently needed. Pulmonary administration is one of the most promising non-parenteral …

The causal relationship between HPV and cervical cancer in association with the high
prevalence of high risk HPV genotypes led to the design of HPV vaccines based on the …