Blood immune profiles reveal a CXCR3/CCR5 axis of dysregulation in early sepsis.

DJ Kealy, JC Wilson, T Jaconelli, K Hogg, R Coop… - medRxiv, 2024 - medrxiv.org
Sepsis is defined as a systemic inflammatory host response syndrome after serious
microbial infection, which requires prompt treatment to lower the risk of complications and …

Quality improvement model (IHI) as a strategy to implement a sepsis protocol in a public hospital in Brazil

LKC Nates, AC Neto, AJ Pereira… - BMJ Open Quality, 2020 - bmjopenquality.bmj.com
A major challenge for hospitals in low-income and middle-income countries is to improve
management of patients diagnosed with sepsis. The objective of the present study was to …

Activity and circadian rhythm of sepsis patients in the intensive care unit

A Davoudi, DB Corbett… - 2018 IEEE EMBS …, 2018 - ieeexplore.ieee.org
Early mobilization of critically ill patients in the Intensive Care Unit (ICU) can prevent
adverse outcomes such as delirium and post-discharge physical impairment. To date, no …

The protective effect of PK-11195 on cognitive impairment in rats survived of polymicrobial sepsis

D Dominguini, AV Steckert, MR Abatti… - Molecular …, 2021 - Springer
Sepsis is an organ dysfunction caused by a host's unregulated response to infection,
causing long-term brain dysfunction with microglial activation, the release of inflammatory …

Development of an e-learning package for sepsis care

A Davis, J Henderson… - British Journal of …, 2016 - magonlinelibrary.com
Severe sepsis is a major cause of morbidity and mortality in the UK. This article describes
the collaborative development and implementation of an interactive online learning package …

[HTML][HTML] Four consecutive yearly point-prevalence studies in Wales indicate lack of improvement in sepsis care on the wards

M Kopczynska, H Unwin, RJ Pugh, B Sharif… - Scientific Reports, 2021 - nature.com
Abstract The 'Sepsis Six'bundle was promoted as a deliverable tool outside of the critical
care settings, but there is very little data available on the progress and change of sepsis care …

Temporal changes of NF-κB signaling pathway genes in bacterial stimulated whole blood-a host mechanism associated with sepsis

A Anirudhan, P Paramasivam, R Murugesan… - Microbial …, 2020 - Elsevier
Bacterial sepsis affects both neonates and adults worldwide. There is no specific anti-sepsis
treatment. Disease management mainly depends on early diagnosis. The gold standard …

[HTML][HTML] Left ventricular dysfunction and reversible pulmonary hypertension secondary to severe pneumonia in a background of sepsis: a case report and review of the …

EN Gitonga, J Wang, S Yu, N Wu… - Annals of Palliative …, 2020 - apm.amegroups.org
Pneumonia is a well-recognized respiratory infection associated with substantial morbidity
and mortality. Despite its effects on the respiratory system, pneumonia can cause or …

Microcirculation alteration and biomarker dilemma in early septic shock diagnosis and treatment

H Al-Ashry, A Abuzaid, M Asim… - Current Vascular …, 2016 - ingentaconnect.com
Introduction: Septic shock is represented by severe hemodynamic changes which are
manifested with failure of organ systems and high mortality. Early diagnosis together with …

Post Caesarean Wound sepsis and associated factors among patients attending a rural regional referral hospital in Western Uganda: A cross-sectional study

I Muhumuza, AZ Lavingia, B Tayebwa, AA Ahmed… - 2020 - researchsquare.com
Background: Post-caesarean wound sepsis is among the most common problem for patients
who undergo caesarean section. It remains a common and widespread problem contributing …