Towards an understanding of the pathological basis of senile depression and incident dementia: Implications for treatment

I Kawakami, J Iga, S Takahashi, YT Lin… - Psychiatry and …, 2022 - Wiley Online Library
Senile depression (SD) is a heterogeneous syndrome. Several clinical profiles are more
likely to appear in SD than in early‐life depression, but it remains unclear whether the …

[HTML][HTML] What makes deprescription of psychotropic drugs in nursing home residents with dementia so challenging? a qualitative systematic review of barriers and …

AE Moth, P Hølmkjær, A Holm, MP Rozing, G Overbeck - Drugs & Aging, 2021 - Springer
Background Behavioral and psychological symptoms of dementia are frequently
experienced in the nursing home setting and place a substantial burden on patients …

Benzodiazepines and antidepressants: Effects on cognitive and functional decline in Alzheimer's disease and Lewy body dementia

MG Borda, A Jaramillo‐Jimenez… - … Journal of Geriatric …, 2021 - Wiley Online Library
Objectives We aim to study the effects of the prescription of benzodiazepines and
antidepressants on cognitive and functional decline in older adults living with Alzheimer's …

[HTML][HTML] Drug delivery approaches for managing overactive bladder (OAB): a systematic review

Z Khizer, A Sadia, R Sharma, S Farhaj, JS Nirwan… - Pharmaceuticals, 2021 - mdpi.com
Overactive bladder syndrome (OAB) is characterised by urgency symptoms, with or without
urgency incontinence, usually with frequency and nocturia and severely affects the quality of …

[HTML][HTML] Carbohydrate polymer-based targeted pharmaceutical formulations for colorectal cancer: Systematic review of the literature

S Farhaj, TL Agbotui, JS Nirwan, Q Mahmood… - Polysaccharides, 2022 - mdpi.com
Colon cancer is the third most diagnosed cancer worldwide, followed by lung and breast
cancer. Conventional treatment methods are associated with numerous side effects and …

National surveillance using a clinical quality indicator for prolonged antipsychotic use among older Australians with dementia who access aged care services

JK Sluggett, GE Caughey, T Air… - … Journal of Geriatric …, 2024 - Wiley Online Library
Objectives Dementia guidelines recommend antipsychotics are only used for behavioral and
psychological symptoms when non‐drug interventions fail, and to regularly review use …

National Trends in Antidepressant Use in Australian Residential Aged Care Facilities (2006–2019)

GA Hughes, MC Inacio, D Rowett, C Lang… - Journal of the American …, 2024 - Elsevier
Objectives Antipsychotics have been the focus of reforms for improving the appropriateness
of psychotropic medicine use in residential aged care facilities (RACFs). Comprehensive …

[HTML][HTML] Short-term risk of unintentional poisoning after new initiation of central nervous system medications in Swedish older adults: a register-based case-crossover …

Y Zhao, Y Liang, L Laflamme, C Rausch, K Johnell… - Drug safety, 2022 - Springer
Introduction Medications acting on the central nervous system (CNS) are common causes of
medication-related unintentional poisoning. Little is known about the short-term effects of …

[HTML][HTML] Effects of central nervous system drugs on androgen, estrogen α, glucocorticoid, and thyroid receptors

M Kenda, T Zore, MS Dolenc - Chemico-biological interactions, 2022 - Elsevier
Some drugs that act on the central nervous system (CNS) are known to affect the endocrine
system, although the mechanisms of endocrine toxicity are not well characterized to date …

Systematic Reviews and Meta-Analysis in Pharmacy Practice

SS Hasan, T Kairuz, K Thiruchelvam… - Pharmacy Practice …, 2020 - Springer
A systematic review is a process of synthesizing research evidence by collecting and
summarizing all empirical evidence that meets predefined inclusion and exclusion criteria …