FLASH ultra-high dose rates in radiotherapy: preclinical and radiobiological evidence
Abstract Purpose Flash radiotherapy (FLASH-RT) is currently being regarded as the next
breakthrough in radiation treatment of cancer, delivering ultrahigh radiation doses in a very …
breakthrough in radiation treatment of cancer, delivering ultrahigh radiation doses in a very …
Back to the future: very high-energy electrons (VHEEs) and their potential application in radiation therapy
MG Ronga, M Cavallone, A Patriarca, AM Leite, P Loap… - Cancers, 2021 - mdpi.com
Simple Summary The development of innovative approaches that would reduce the
sensitivity of healthy tissues to irradiation while maintaining the efficacy of the treatment on …
sensitivity of healthy tissues to irradiation while maintaining the efficacy of the treatment on …
An experimental study of focused very high energy electron beams for radiotherapy
K Kokurewicz, E Brunetti, A Curcio, D Gamba… - Communications …, 2021 - nature.com
Very high energy electron (VHEE) beams have been proposed as an alternative
radiotherapy modality to megavoltage photons; they penetrate deeply without significant …
radiotherapy modality to megavoltage photons; they penetrate deeply without significant …
Gev-scale accelerators driven by plasma-modulated pulses from kilohertz lasers
O Jakobsson, SM Hooker, R Walczak - Physical Review Letters, 2021 - APS
We describe a new approach for driving GeV-scale plasma accelerators with long laser
pulses. We show that the temporal phase of a long, high-energy driving laser pulse can be …
pulses. We show that the temporal phase of a long, high-energy driving laser pulse can be …
A focused very high energy electron beam for fractionated stereotactic radiotherapy
An electron beam of very high energy (50–250 MeV) can potentially produce a more
favourable radiotherapy dose distribution compared to a state-of-the-art photon based …
favourable radiotherapy dose distribution compared to a state-of-the-art photon based …
Free electron lasers driven by plasma accelerators: status and near-term prospects
Owing to their ultra-high accelerating gradients, combined with injection inside micrometer-
scale accelerating wakefield buckets, plasma-based accelerators hold great potential to …
scale accelerating wakefield buckets, plasma-based accelerators hold great potential to …
Linear colliders based on laser-plasma accelerators
C Benedetti, SS Bulanov, E Esarey… - arXiv preprint arXiv …, 2022 - arxiv.org
arXiv:2203.08366v2 [physics.acc-ph] 4 Jul 2022 Page 1 White paper to the Proceedings of the
US Particle Physics Community Planning Exercise (Snowmass 2021): Linear colliders based …
US Particle Physics Community Planning Exercise (Snowmass 2021): Linear colliders based …
Linear colliders based on laser-plasma accelerators
Laser-plasma accelerators are capable of sustaining accelerating fields of 10–100 GeV/m,
100–1000 times that of conventional technology and the highest fields produced by any of …
100–1000 times that of conventional technology and the highest fields produced by any of …
Tuning curves for a laser-plasma accelerator
Applications of laser-plasma accelerators (LPA) require independent control of electron
beam parameters. However, due to the complex coupling of the many variables governing …
beam parameters. However, due to the complex coupling of the many variables governing …
Transformative technology for FLASH radiation therapy: A snowmass 2021 white paper
S Boucher, E Esarey, C Geddes, C Johnstone… - arXiv preprint arXiv …, 2022 - arxiv.org
Conventional cancer therapies include surgery, radiation therapy, chemotherapy, and, more
recently, immunotherapy. These modalities are often combined to improve the therapeutic …
recently, immunotherapy. These modalities are often combined to improve the therapeutic …