Preparation of trans-Crocetin with High Solubility, Stability, and Oral Bioavailability by Incorporation into Three Types of Cyclodextrins

N Liu, J Xiao, LH Zang, P Quan, DC Liu - Pharmaceutics, 2023 - mdpi.com
Crocetin (CRT), an active compound isolated from saffron, exhibits several pharmacological
activities, including anti-tumor and immune-regulatory activities, and is effective against …

Randomized, Double-Blind, Placebo-Controlled Clinical Trial of Concurrent Use of Crocin During Chemoradiation for Esophageal Squamous Cell Carcinoma

N Ebrahimi, SA Javadinia, R Salek… - Cancer …, 2024 - Taylor & Francis
Crocin is the major active carotenoid of saffron (Crocus sativus L.). Its pluripotent effects
have led to a growing body of literature investigating its antitumor properties as well as its …

Crocin inhibit the metastasis of MDA-MB-231 cell line by suppressing epithelial to mesenchymal transition through WNT/β-catenin signalling pathway

V Ghorbanzadeh, KAH Aljaf, HM Wasman… - Annals of Medicine …, 2024 - journals.lww.com
Background: Triple-negative breast cancer has the poorest prognosis and survival rates
compared to other breast cancer subtypes due to its invasive behaviours. This type of cancer …