A century ago, Cajal noted striking similarities between the neural circuits that underlie
vision in vertebrates and flies. Over the past few decades, structural and functional studies …

Originally a genetic model organism, the experimental use of Drosophila melanogaster has
grown to include quantitative behavioral analyses, sophisticated perturbations of neuronal …

We describe the development and application of methods for high-throughput
neuroanatomy in Drosophila using light microscopy. These tools enable efficient multicolor …

The anatomy of many neural circuits is being characterized with increasing resolution, but
their molecular properties remain mostly unknown. Here, we characterize gene expression …

Visual projection neurons (VPNs) provide an anatomical connection between early visual
processing and higher brain regions. Here we characterize lobula columnar (LC) cells, a …

Genetically encoded effectors are important tools for probing cellular function in living
animals, but improved methods for directing their expression to specific cell types are …

Sparse coding may be a general strategy of neural systems for augmenting memory
capacity. In Drosophila melanogaster, sparse odor coding by the Kenyon cells of the …

Research in the fruit fly Drosophila melanogaster has led to insights in neural development,
axon guidance, ion channel function, synaptic transmission, learning and memory, diurnal …

Many insects use patterns of polarized light in the sky to orient and navigate. Here, we
functionally characterize neural circuitry in the fruit fly, Drosophila melanogaster, that …

Motion vision is a major function of all visual systems, yet the underlying neural mechanisms
and circuits are still elusive. In the lamina, the first optic neuropile of Drosophila …