The search for noise-induced cochlear synaptopathy in humans: Mission impossible?
N Bramhall, EF Beach, B Epp, CG Le Prell… - Hearing research, 2019 - Elsevier
Animal studies demonstrate that noise exposure can permanently damage the synapses
between inner hair cells and auditory nerve fibers, even when outer hair cells are intact and …
between inner hair cells and auditory nerve fibers, even when outer hair cells are intact and …
Occupational noise: auditory and non-auditory consequences
Occupational noise exposure accounts for approximately 16% of all disabling hearing
losses, but the true value and societal costs may be grossly underestimated because current …
losses, but the true value and societal costs may be grossly underestimated because current …
Middle ear muscle reflex and word recognition in “normal-hearing” adults: evidence for cochlear synaptopathy?
AM Mepani, SA Kirk, KE Hancock, K Bennett… - Ear and …, 2020 - journals.lww.com
Objectives: Permanent threshold elevation after noise exposure, ototoxic drugs, or aging is
caused by loss of sensory cells; however, animal studies show that hair cell loss is often …
caused by loss of sensory cells; however, animal studies show that hair cell loss is often …
Hidden hearing loss: a disorder with multiple etiologies and mechanisms
DC Kohrman, G Wan… - Cold Spring …, 2020 - perspectivesinmedicine.cshlp.org
Hidden hearing loss (HHL), a recently described auditory disorder, has been proposed to
affect auditory neural processing and hearing acuity in subjects with normal audiometric …
affect auditory neural processing and hearing acuity in subjects with normal audiometric …
Electrophysiological markers of cochlear function correlate with hearing-in-noise performance among audiometrically normal subjects
KJ Grant, AM Mepani, P Wu… - Journal of …, 2020 - journals.physiology.org
Hearing loss caused by noise exposure, ototoxic drugs, or aging results from the loss of
sensory cells, as reflected in audiometric threshold elevation. Animal studies show that loss …
sensory cells, as reflected in audiometric threshold elevation. Animal studies show that loss …
Effects of noise exposure on auditory brainstem response and speech-in-noise tasks: A review of the literature
CG Le Prell - International journal of audiology, 2019 - Taylor & Francis
Objective: Short-term noise exposure that induces transient changes in thresholds has
induced permanent cochlear synaptopathy in multiple species. Here, the literature was …
induced permanent cochlear synaptopathy in multiple species. Here, the literature was …
Working memory and extended high-frequency hearing in adults: Diagnostic predictors of speech-in-noise perception
I Yeend, EF Beach, M Sharma - Ear and Hearing, 2019 - journals.lww.com
Objective: The purpose of this study was to identify the main factors that differentiate
listeners with clinically normal or “near-normal” hearing with regard to their speech-in-noise …
listeners with clinically normal or “near-normal” hearing with regard to their speech-in-noise …
Alterations in auditory brain stem response distinguish occasional and constant tinnitus
BACKGROUND The heterogeneity of tinnitus is thought to underlie the lack of objective
diagnostic measures. METHODS Longitudinal data from 20,349 participants of the Swedish …
diagnostic measures. METHODS Longitudinal data from 20,349 participants of the Swedish …
[HTML][HTML] Associations between speech recognition at high levels, the middle ear muscle reflex and noise exposure in individuals with normal audiograms
It has been hypothesized that noise-induced cochlear synaptopathy in humans may result in
functional deficits such as a weakened middle ear muscle reflex (MEMR) and degraded …
functional deficits such as a weakened middle ear muscle reflex (MEMR) and degraded …
[HTML][HTML] Investigating the effects of noise exposure on self-report, behavioral and electrophysiological indices of hearing damage in musicians with normal audiometric …
Musicians are at risk of hearing loss due to prolonged noise exposure, but they may also be
at risk of early sub-clinical hearing damage, such as cochlear synaptopathy. In the current …
at risk of early sub-clinical hearing damage, such as cochlear synaptopathy. In the current …