[HTML][HTML] WNT signaling in stem cells: A look into the non-canonical pathway
MA Sarabia-Sánchez, M Robles-Flores - Stem Cell Reviews and Reports, 2024 - Springer
Tissue homeostasis is crucial for multicellular organisms, wherein the loss of cells is
compensated by generating new cells with the capacity for proliferation and differentiation …
compensated by generating new cells with the capacity for proliferation and differentiation …
Cell-intrinsic factors governing quiescence vis-a-vis activation of adult hematopoietic stem cells
Hematopoiesis is a highly complex process, regulated by both intrinsic and extrinsic factors.
Often, these two regulatory arms work in tandem to maintain the steady-state condition of …
Often, these two regulatory arms work in tandem to maintain the steady-state condition of …
[HTML][HTML] The maintenance mechanism of hematopoietic stem cell dormancy: role for a subset of macrophages
CW Chae, G Choi, YJ Kim, M Cho, YW Kwon… - BMB reports, 2023 - ncbi.nlm.nih.gov
Hematopoiesis is regulated by crosstalk between long-term repopulating hematopoietic
stem cells (LT-HSCs) and supporting niche cells in the bone marrow (BM). Here, we …
stem cells (LT-HSCs) and supporting niche cells in the bone marrow (BM). Here, we …
Kinase-inactivated CDK6 preserves the long-term functionality of adult hematopoietic stem cells
IM Mayer, E Doma, T Klampfl, M Prchal-Murphy… - Blood, 2024 - ashpublications.org
Hematopoietic stem cells (HSCs) are characterized by the ability to self-renew and to
replenish the hematopoietic system. The cell-cycle kinase cyclin-dependent kinase 6 …
replenish the hematopoietic system. The cell-cycle kinase cyclin-dependent kinase 6 …
Ex vivo expansion of hematopoietic stem cells in two/three-dimensional co-cultures with various source of stromal cells
The ex vivo expansion of hematopoietic stem cells, with both high quantities and quality, is
considered a paramount issue in cell and gene therapy for hematological diseases …
considered a paramount issue in cell and gene therapy for hematological diseases …
Impact of the overexpression of the tyrosine kinase receptor RET in the hematopoietic potential of induced pluripotent stem cells (iPSCs)
P Marcoux, J Imeri, C Desterke, T Latsis, D Chaker… - Cytotherapy, 2024 - Elsevier
Introduction Previous studies have suggested that the tyrosine kinase receptor RET plays a
significant role in the hematopoietic potential in mice and could also be used to expand cord …
significant role in the hematopoietic potential in mice and could also be used to expand cord …
Phenotypic Analysis of Hematopoietic Stem and Progenitor Cell Populations in Acute Myeloid Leukemia Based on Spectral Flow Cytometry, a 20-Color Panel, and …
T Matthes - International Journal of Molecular Sciences, 2024 - mdpi.com
The analysis of hematopoietic stem and progenitor cell populations (HSPCs) is fundamental
in the understanding of normal hematopoiesis as well as in the management of malignant …
in the understanding of normal hematopoiesis as well as in the management of malignant …
Oncoproteomics: insight into current proteomic technologies in cancer biomarker discovery and treatment
Cancer is a disease with second largest fatalities in humans and the sheer complexity of the
disease is an enigma to the scientific community. It continues to be a highly significant …
disease is an enigma to the scientific community. It continues to be a highly significant …
[PDF][PDF] Insulin-producing cells in the treatment of type 1 diabetes: a literature review
N Karakursakov, VY Mikhailichenko… - Archiv …, 2022 - journal-archiveuromedica.eu
This review discusses the prospects for the treatment of insulin-dependent diabetes mellitus.
The use of insulin-producing cells of various origins is relevant and may in the future replace …
The use of insulin-producing cells of various origins is relevant and may in the future replace …
RET-altered Induced Pluripotent Stem Cells (iPSCs) for modeling Hematopoiesis and Non-Small Cell Lung Cancer (NSCLC)
P Marcoux - 2023 - theses.hal.science
Induced pluripotent stem cells (iPSCs) are generated by reprogramming adult cells back into
an embryonic-like state. iPSCs can be differentiated into various cell types, making them a …
an embryonic-like state. iPSCs can be differentiated into various cell types, making them a …