[HTML][HTML] Virulence evolution, molecular mechanisms of resistance and prevalence of ST11 carbapenem-resistant Klebsiella pneumoniae in China: a review over the …

W Liao, Y Liu, W Zhang - Journal of global antimicrobial resistance, 2020 - Elsevier
ST11 carbapenem-resistant K. pneumoniae (CRKP) has been the dominant clone in China.
In this review, we trace the prevalence of ST11 CRKP in China Antimicrobial Surveillance …

Antibiotic Heteroresistance in Klebsiella pneumoniae

K Stojowska-Swędrzyńska, A Łupkowska… - International journal of …, 2021 - mdpi.com
Klebsiella pneumoniae is one of the most common pathogens responsible for infections,
including pneumonia, urinary tract infections, and bacteremias. The increasing prevalence …

Emergence and Recovery of Ceftazidime-avibactam Resistance in blaKPC-33-Harboring Klebsiella pneumoniae Sequence Type 11 Isolates in China

Q Shi, D Yin, R Han, Y Guo, Y Zheng… - Clinical Infectious …, 2020 - academic.oup.com
This is the first report of ceftazidime–avibactam resistance caused by the bla KPC-33
mutation through the D179Y variant during the treatment of bla KPC-2-positive Klebsiella …

[HTML][HTML] Antibiotic therapy for pan-drug-resistant infections

MA Ozma, A Abbasi, M Asgharzadeh… - Le infezioni in …, 2022 - ncbi.nlm.nih.gov
Antibiotic resistance occurs when microorganisms resist the drugs used against the infection
caused by them and neutralize their effects over time using various mechanisms. These …

The Plasmid-Borne tet(A) Gene Is an Important Factor Causing Tigecycline Resistance in ST11 Carbapenem-Resistant Klebsiella pneumoniae Under Selective …

J Xu, Z Zhu, Y Chen, W Wang, F He - Frontiers in Microbiology, 2021 - frontiersin.org
The emergence and prevalence of tigecycline-resistant Klebsiella pneumoniae have
seriously compromised the effectiveness of antimicrobial agents in the treatment of …

Klebsiella pneumoniae bacteraemia epidemiology: resistance profiles and clinical outcome of King Fahad Medical City isolates, Riyadh, Saudi Arabia

TA Hafiz, S Alanazi, SS Alghamdi, MA Mubaraki… - BMC infectious …, 2023 - Springer
Background and objectives Klebsiella pneumoniae (K. pneumoniae) is the second leading
cause of community-acquired and hospital-acquired gram-negative bloodstream infection …

CRISPR-cas, a revolution in the treatment and study of ESKAPE infections: pre-clinical studies

M González de Aledo, M González-Bardanca, L Blasco… - Antibiotics, 2021 - mdpi.com
One of the biggest threats we face globally is the emergence of antimicrobial-resistant
(AMR) bacteria, which runs in parallel with the lack in the development of new …

Characterization of Tigecycline Resistance Among Tigecycline Non-susceptible Klebsiella pneumoniae Isolates From Humans, Food-Producing Animals, and in vitro …

M Moghimi, M Haeili, H Mohajjel Shoja - Frontiers in Microbiology, 2021 - frontiersin.org
Emergence of extensively drug-resistant isolates of Klebsiella pneumoniae has prompted
increased reliance on the last-resort antibiotics such as tigecycline (TGC) for treating …

Phenotypic and Genotypic Characterization of Pan-Drug-Resistant Klebsiella pneumoniae Isolated in Qatar

MA Sid Ahmed, JM Hamid, AMM Hassan, S Abu Jarir… - Antibiotics, 2024 - mdpi.com
In secondary healthcare, carbapenem-resistant Enterobacterales (CREs), such as those
observed in Klebsiella pneumoniae, are a global public health priority with significant …

[HTML][HTML] Screening of MMV pandemic response and pathogen box compounds against pan-drug-resistant Klebsiella pneumoniae to identify potent inhibitory …

S Sivasankar, MA Premnath, A Boppe… - New Microbes and New …, 2023 - Elsevier
Background The recent emergence of pan-drug-resistant (PDR) K. pneumoniae strains
hinders the success rate of treatment procedures for patients. High mortality, extended …