Natural and synthetic flavonoid derivatives as new potential tyrosinase inhibitors: A systematic review

RJ Obaid, EU Mughal, N Naeem, A Sadiq… - RSC …, 2021 - pubs.rsc.org
Tyrosinase is a multifunctional glycosylated and copper-containing oxidase that is highly
prevalent in plants and animals and plays a pivotal role in catalyzing the two key steps of …

Natural products in cosmetics

JK Liu - Natural products and bioprospecting, 2022 - Springer
The global cosmetics market reached US 500billionin2017andisexpectedtoexceedUS 800
billion by 2023, at around a 7% annual growth rate. The cosmetics industry is emerging as …

Natural, semisynthetic and synthetic tyrosinase inhibitors

SY Lee, N Baek, T Nam - Journal of Enzyme Inhibition and …, 2016 - Taylor & Francis
Tyrosinase plays a pivotal role in the synthesis of melanin pigment synthesis on skin utilizing
tyrosine as a substrate. Melanin is responsible for the protection against harmful ultraviolet …

Tyrosinase inhibitors from natural and synthetic sources: structure, inhibition mechanism and perspective for the future

YJ Kim, H Uyama - Cellular and molecular life sciences CMLS, 2005 - Springer
Tyrosinase is known to be a key enzyme in melanin biosynthesis, involved in determining
the color of mammalian skin and hair. Various dermatological disorders, such as melasma …

Mushroom tyrosinase: recent prospects

SY Seo, VK Sharma, N Sharma - Journal of agricultural and food …, 2003 - ACS Publications
Tyrosinase, also known as polyphenol oxidase, is a copper-containing enzyme, which is
widely distributed in microorganisms, animals, and plants. Nowadays mushroom tyrosinase …

Flavonols from Heterotheca inuloides: tyrosinase inhibitory activity and structural criteria

I Kubo, I Kinst-Hori, SK Chaudhuri, Y Kubo… - Bioorganic & medicinal …, 2000 - Elsevier
Tyrosinase inhibitory activity of flavonols, galangin, kaempferol and quercetin, was found to
come from their ability to chelate copper in the enzyme. In contrast, the corresponding …

Flavonols from saffron flower: tyrosinase inhibitory activity and inhibition mechanism

I Kubo, I Kinst-Hori - Journal of agricultural and food chemistry, 1999 - ACS Publications
A common flavonol, kaempferol, isolated from the fresh flower petals of Crocus sativus
L.(Iridaceae) was found to inhibit the oxidation of l-3, 4-dihydroxyphenylalanine (l-DOPA) …

Tyrosinase inhibition: general and applied aspects

A Rescigno, F Sollai, B Pisu, A Rinaldi… - Journal of Enzyme …, 2002 - Taylor & Francis
The active site of tyrosinase is described with a view to depicting its interactions with
substrates and inhibitors. Occurrence and mechanism (s) of tyrosinase-mediated browning …

Natural products with skin-whitening effects

JW Lin, HM Chiang, YC Lin, KC Wen - Journal of Food and Drug …, 2008 - jfda-online.com
UV radiation is widely considered as a major cause of skin pigmentation. Upon exposure to
UV radiation, the melanocytes increase the production of intracellular nitric oxide, which …

New applications for phytochemical pest-control agents

PA Hedin, RM Hollingworth - 1997 - ACS Publications
Natural products from plants continue to be the subject of novel and straightforward
applications as pest control agents. It is noteworthy that these agents are perhaps most often …