[HTML][HTML] Cancer cell-intrinsic XBP1 drives immunosuppressive reprogramming of intratumoral myeloid cells by promoting cholesterol production
Z Yang, Y Huo, S Zhou, J Guo, X Ma, T Li, C Fan… - Cell Metabolism, 2022 - cell.com
A hostile microenvironment in tumor tissues disrupts endoplasmic reticulum homeostasis
and induces the unfolded protein response (UPR). A chronic UPR in both cancer cells and …
and induces the unfolded protein response (UPR). A chronic UPR in both cancer cells and …
[HTML][HTML] Extracellular vesicles: new classification and tumor immunosuppression
Simple Summary Extracellular vesicles (EVs) are cell-derived membrane-surrounded
vesicles that carry bioactive molecules and deliver them to recipient cells. Classical EVs are …
vesicles that carry bioactive molecules and deliver them to recipient cells. Classical EVs are …
A comparison of cellular uptake mechanisms, delivery efficacy, and intracellular fate between liposomes and extracellular vesicles
TB Gandek, L van der Koog… - Advanced healthcare …, 2023 - Wiley Online Library
A key aspect for successful drug delivery via lipid‐based nanoparticles is their
internalization in target cells. Two prominent examples of such drug delivery systems are …
internalization in target cells. Two prominent examples of such drug delivery systems are …
[HTML][HTML] The crosstalk: Exosomes and lipid metabolism
W Wang, N Zhu, T Yan, YN Shi, J Chen… - Cell Communication and …, 2020 - Springer
Exosomes have been considered as novel and potent vehicles of intercellular
communication, instead of “cell dust”. Exosomes are consistent with anucleate cells, and …
communication, instead of “cell dust”. Exosomes are consistent with anucleate cells, and …
Engineering extracellular vesicles restore the impaired cellular uptake and attenuate intervertebral disc degeneration
Z Liao, H Liu, L Ma, J Lei, B Tong, G Li, W Ke, K Wang… - ACS …, 2021 - ACS Publications
Extracellular vesicles (EVs) are potential alternatives for mesenchymal stem cells (MSCs) in
the treatment of musculoskeletal degenerative diseases, including intervertebral disc …
the treatment of musculoskeletal degenerative diseases, including intervertebral disc …
Internalization of exosomes through receptor-mediated endocytosis
The tumor microenvironment is replete with factors secreted and internalized by surrounding
cells. Exosomes are nano-sized, protein-embedded, membrane-bound vesicles that are …
cells. Exosomes are nano-sized, protein-embedded, membrane-bound vesicles that are …
Apoptotic bodies for advanced drug delivery and therapy
M Zhou, YJ Li, YC Tang, XY Hao, WJ Xu… - Journal of Controlled …, 2022 - Elsevier
Extracellular vesicles (EVs) have emerged as promising candidates for multiple biomedical
applications. Major types of EVs include exosomes, microvesicles, and apoptotic bodies …
applications. Major types of EVs include exosomes, microvesicles, and apoptotic bodies …
[HTML][HTML] Exosomes as drug carriers for cancer therapy and challenges regarding exosome uptake
X Zhao, D Wu, X Ma, J Wang, W Hou… - Biomedicine & …, 2020 - Elsevier
With the development of biomedicine, exosomes are rapidly developing as a new therapy
for tumors. As biological carriers, exosomes possess biological activity and can transport …
for tumors. As biological carriers, exosomes possess biological activity and can transport …
[HTML][HTML] Extracellular vesicles as bioactive nanotherapeutics: an emerging paradigm for regenerative medicine
In recent decades, extracellular vesicles (EVs), as bioactive cell-secreted nanoparticles
which are involved in various physiological and pathological processes including cell …
which are involved in various physiological and pathological processes including cell …
Mesenchymal stem cell-derived extracellular vesicles and retinal ischemia-reperfusion
Retinal ischemia is a major cause of vision loss and impairment and a common underlying
mechanism associated with diseases such as glaucoma, diabetic retinopathy, and central …
mechanism associated with diseases such as glaucoma, diabetic retinopathy, and central …