p28-functionalized PLGA nanoparticles loaded with gefitinib reduce tumor burden and metastases formation on lung cancer
Lung cancer is still the main cause of cancer-related deaths worldwide. Its treatment
generally includes surgical resection, immunotherapy, radiotherapy, and chemo-targeted …
generally includes surgical resection, immunotherapy, radiotherapy, and chemo-targeted …
Neurons can upregulate Cav-1 to increase intake of endothelial cells-derived extracellular vesicles that attenuate apoptosis via miR-1290
KY Yue, PR Zhang, MH Zheng, XL Cao, Y Cao… - Cell death & …, 2019 - nature.com
Extracellular vesicles (EVs) including exosomes can serve as mediators of cell–cell
communication under physiological and pathological conditions. However, cargo molecules …
communication under physiological and pathological conditions. However, cargo molecules …
A role for extracellular vesicles in SARS-CoV-2 therapeutics and prevention
Extracellular vesicles (EVs) are the common designation for ectosomes, microparticles and
microvesicles serving dominant roles in intercellular communication. Both viable and dying …
microvesicles serving dominant roles in intercellular communication. Both viable and dying …
Trophoblast derived extracellular vesicles specifically alter the transcriptome of endometrial cells and may constitute a critical component of embryo-maternal …
Background The period of time when the embryo and the endometrium undergo significant
morphological alterations to facilitate a successful implantation—known as “window of …
morphological alterations to facilitate a successful implantation—known as “window of …
Uptake and fate of extracellular membrane vesicles: nucleoplasmic reticulum-associated late endosomes as a new gate to intercellular communication
Extracellular membrane vesicles (EVs) are emerging as new vehicles in intercellular
communication, but how the biological information contained in EVs is shared between cells …
communication, but how the biological information contained in EVs is shared between cells …
Extracellular vesicles and oncogenic signaling
A Schubert, M Boutros - Molecular oncology, 2021 - Wiley Online Library
In recent years, extracellular vesicles (EVs) emerged as potential diagnostic and prognostic
markers for cancer therapy. While the field of EV research is rapidly developing and their …
markers for cancer therapy. While the field of EV research is rapidly developing and their …
[HTML][HTML] Mesenchymal stem cell-derived exosomes: The dawn of diabetic wound healing
J Wu, LH Chen, SY Sun, Y Li, XW Ran - World Journal of Diabetes, 2022 - ncbi.nlm.nih.gov
Chronic wound healing has long been an unmet medical need in the field of wound repair,
with diabetes being one of the major etiologies. Diabetic chronic wounds (DCWs), especially …
with diabetes being one of the major etiologies. Diabetic chronic wounds (DCWs), especially …
Extracellular vesicles as drug delivery vehicles to the central nervous system
Effective drug delivery to the CNS to achieve the desired therapeutic response is a
significant challenge in the field of drug delivery. In central nervous system (CNS), blood …
significant challenge in the field of drug delivery. In central nervous system (CNS), blood …
Cell Membrane‐Anchoring Nano‐Photosensitizer for Light‐Controlled Calcium‐Overload and Tumor‐Specific Synergistic Therapy
M Gao, T Yang, W Qin, Q Wang, M Huang, H Peng… - Small, 2022 - Wiley Online Library
Poor selectivity and unintended toxicity to normal organs are major challenges in calcium
ion (Ca2+) overload tumor therapy. To address this issue, a cell membrane‐anchoring nano …
ion (Ca2+) overload tumor therapy. To address this issue, a cell membrane‐anchoring nano …
Ultrasound facilitates naturally equipped exosomes derived from macrophages and blood serum for orthotopic glioma treatment
L Bai, Y Liu, K Guo, K Zhang, Q Liu… - … applied materials & …, 2019 - ACS Publications
Exosomes (Exos) are endogenous nanocarriers that have utility as novel delivery systems
for the treatment of brain cancers. However, in general, natural Exos show limited BBB …
for the treatment of brain cancers. However, in general, natural Exos show limited BBB …