Indole and its derivatives are widespread across different life forms, functioning as signalling
molecules in prokaryotes and with more diverse roles in eukaryotes. A majority of indoles …

Diabetes contributes to the onset of various diseases, including cancer and cardiovascular
and neurodegenerative diseases. Recent studies have highlighted the similarities and …

Chronic kidney disease (CKD) affects about 10% of all populations worldwide, with about 2
million people requiring dialysis. Although patients with CKD are at high risk of …

Hippuric acid (HA) is a metabolite resulting from the hepatic glycine conjugation of benzoic
acid (BA) or from the gut bacterial metabolism of phenylalanine. BA is generally produced by …

Diabetes mellitus (DM) is an endemic disease, with growing health and social costs. The
complications of diabetes can affect potentially all parts of the human body, from the heart to …

Intracranial aneurysms (IA) are the most common cerebral vascular pathologies. Their
rupture leads to the most dangerous subtype of stroke—aneurysmal subarachnoid …

In the last decade, metagenomic studies have shown the key role of the gut microbiome in
maintaining immune and neuroendocrine systems. Malfunction of the gut microbiome can …

The gut microbiome plays a major role in human health, and gut microbial imbalance or
dysbiosis is associated with disease development. Modulation in the gut microbiome can be …

The gut microbiome helps maintain homeostasis in the body, but what if the gut experiences
imbalance? It would lead to dysbiosis-which is involved in multiple diseases, including but …

Aims: Recent studies hypothesized a role of gut microbiota favoring atherosclerosis via an
increased oxidative stress, but data in peripheral artery disease (PAD) have not been …