[HTML][HTML] T cell antifungal immunity and the role of C-type lectin receptors

EA Speakman, IM Dambuza, F Salazar, GD Brown - Trends in immunology, 2020 - cell.com
Fungi can cause disease in humans, from mucocutaneous to life-threatening systemic
infections. Initiation of antifungal immunity involves fungal recognition by pattern recognition …

[HTML][HTML] Neutrophils: Musketeers against immunotherapy

KR Zahid, U Raza, S Tumbath, L Jiang, W Xu… - Frontiers in …, 2022 - frontiersin.org
Neutrophils, the most copious leukocytes in human blood, play critical role in tumorigenesis,
cancer progression and immune suppression. Recently, neutrophils have attracted attention …

Neutrophil extracellular traps induced by IL-8 aggravate atherosclerosis via activation NF-κB signaling in macrophages

Z An, J Li, J Yu, X Wang, H Gao, W Zhang, Z Wei… - Cell Cycle, 2019 - Taylor & Francis
Here, we sought to explore the underlying role of interleukin (IL)-8 in neutrophil extracellular
traps (NETs) formation during atherosclerosis (AS). The concentration of pro-inflammatory …

[HTML][HTML] Vaccine protection by Cryptococcus neoformans Δsgl1 is mediated by γδ T cells via TLR2 signaling

TG Normile, TH Chu, BS Sheridan, M Del Poeta - Mucosal immunology, 2022 - Elsevier
We previously reported that administration of Cryptococcus neoformans Δsgl1 mutant
vaccine, accumulating sterylglucosides (SGs) and having normal capsule (GXM), protects …

[HTML][HTML] Immune Response in Pneumocystis Infections According to the Host Immune System Status

E Charpentier, S Ménard, C Marques, A Berry, X Iriart - Journal of Fungi, 2021 - mdpi.com
The host immune response is critical in Pneumocystis pneumonia (PCP). Immunocompetent
hosts can eliminate the fungus without symptoms, while immunodeficient hosts develop PCP …

[HTML][HTML] The Contribution of Host Cells to Pneumocystis Immunity: An Update

P Otieno-Odhiambo, S Wasserman, JC Hoving - Pathogens, 2019 - mdpi.com
Pneumocystis is a ubiquitous atypical fungus that is distributed globally. The genus
comprises morphologically similar but genetically heterogeneous species that have co …

PD-1 Deficiency Promotes Macrophage Activation and T-Helper Cell Type 1/T-Helper Cell Type 17 Response in Pneumocystis Pneumonia

C Zhang, HM Rong, T Li, K Zhai… - American Journal of …, 2020 - atsjournals.org
Pneumocystis is an unusual, opportunistic fungal pathogen capable of causing
Pneumocystis pneumonia (PCP) in immunocompromised hosts. Although PCP was …

[HTML][HTML] Single-cell TCR sequencing reveals the dynamics of T cell repertoire profiling during pneumocystis infection

HQ Yang, YS Wang, K Zhai, ZH Tong - Frontiers in Microbiology, 2021 - frontiersin.org
T cell responses play critical roles in host adaptive immunity against Pneumocystis.
However, the dynamics and diversity of the T cell immune repertoire in human …

Upregulated expression of the IL-9 receptor on TRAF3-deficient B lymphocytes confers ig isotype switching responsiveness to IL-9 in the presence of antigen receptor …

S Gokhale, E Victor, J Tsai, E Spirollari… - The Journal of …, 2023 - journals.aai.org
The pleiotropic cytokine IL-9 signals to target cells by binding to a heterodimeric receptor
consisting of the unique subunit IL-9R and the common subunit γ-chain shared by multiple …

[HTML][HTML] Early diagnosis of psoriatic arthritis among psoriasis patients: clinical experience sharing

YJ Su - Clinical Rheumatology, 2020 - Springer
Background The early detection of psoriatic arthritis (PSA) poses a challenge to
rheumatologists, even when their diagnosis is aided by sonography. In order to facilitate …