The incidence of infections caused by Candida species (candidosis) has increased
considerably over the past three decades, mainly due to the rise of the AIDS epidemic, an …

Aspergillus fumigatus is one of the most ubiquitous of the airborne saprophytic fungi.
Humans and animals constantly inhale numerous conidia of this fungus. The conidia are …

The increased use of antibacterial and antifungal agents in recent years has resulted in the
development of resistance to these drugs. The significant clinical implication of resistance …

Although Cryptococcus neoformans and cryptococcosis have existed for several millennia, a
century has passed since the discovery of this encapsulated yeast and its devastating …

The availability of new antifungal agents with novel mechanisms of action has stimulated
renewed interest in combination antifungal therapies. In particular, and despite the limited …

Aspergillus infections are occurring with an increasing frequency in transplant recipients.
Notable changes in the epidemiologic characteristics of this infection have occurred; these …

Fungal infections are a major burden to the health and welfare of modern humans. They
range from simply cosmetic, non-life-threatening skin infections to severe, systemic …

No controlled trials of therapy for invasive aspergillosis have been done. This review
appraises 2,121 cases reported in 497 articles in the literature and analyzes 440 courses of …

Cryptococcus neoformans strains classically have been grouped into two varieties that
included five serotypes known as C. neoformans variety neoformans (serotypes A, D, and …

Much progress has been made in the last decade in identifying genes responsible for
antifungal resistance in Candida albicans. Attention has focused on five major C. albicans …