Aging is characterized by systemic chronic inflammation, which is accompanied by cellular
senescence, immunosenescence, organ dysfunction, and age-related diseases. Given the …

Aging is characterized by a progressive deterioration of physiological integrity, leading to
impaired functional ability and ultimately increased susceptibility to death. It is a major risk …

The population is aging at a rate never seen before in human history. As the number of
elderly adults grows, it is imperative we expand our understanding of the underpinnings of …

Lung aging is associated with structural remodeling, a decline of respiratory function and a
higher susceptibility to acute and chronic lung diseases. Individual factors that modulate …

Prevalence of asthma in older adults is growing along with increasing global life expectancy.
Due to poor clinical consequences such as high mortality, advancement in understanding …

The lungs face ongoing chemical, mechanical, biological, immunological and xenobiotic
stresses over a lifetime. Advancing age progressively impairs lung function. Autophagy is a …

Aging biomarkers are a combination of biological parameters to (i) assess age-related
changes,(ii) track the physiological aging process, and (iii) predict the transition into a …

The prevalence of lung conditions, such as COPD and pulmonary fibrosis, and lung
infections, such as pneumonia, increases sharply with age. The physiologic, cellular, and …

Aging is associated with a dysregulation of the immune system, leading to a general pro-
inflammatory state of the organism, a process that has been named inflamm-aging …

Respiratory infections pose a significant health problem among elderly individuals,
particularly during the COVID-19 pandemic. The increased mortality and morbidity rates …