The AID/APOBEC polynucleotide cytidine deaminases have historically been classified as
either DNA mutators or RNA editors based on their first identified nucleic acid substrate …

Various next generation sequencing (NGS) based strategies have been successfully used in
the recent past for tracing origins and understanding the evolution of infectious agents …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has undergone
progressive change, with variants conferring advantage rapidly becoming dominant …

Neutralizing antibodies against the SARS-CoV-2 spike (S) protein are a goal of COVID-19
vaccines and have received emergency use authorization as therapeutics. However, viral …

Background A novel coronavirus (CoV), severe acute respiratory syndrome (SARS)–CoV-2,
has infected> 75 000 individuals and spread to> 20 countries. It is still unclear how fast the …

Background and Aims Cancer‐associated fibroblasts (CAFs) are key players in multicellular,
stromal‐dependent alterations leading to HCC pathogenesis. However, the intricate …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has killed millions of
people and continues to cause massive global upheaval. Coronaviruses are positive-strand …

Coronaviruses (CoVs) stand out for their large RNA genome and complex RNA-synthesizing
machinery comprising 16 nonstructural proteins (nsps). The bifunctional nsp14 contains 3 …

Coronaviruses (CoVs) have emerged from animal reservoirs to cause severe and lethal
disease in humans, but there are currently no FDA-approved antivirals to treat the infections …

Viral quasispecies refers to a population structure that consists of extremely large numbers
of variant genomes, termed mutant spectra, mutant swarms or mutant clouds. Fueled by high …