Deciphering the role of HPV-mediated metabolic regulation in shaping the tumor microenvironment and its implications for immunotherapy in HNSCC

X Gong, J Xiong, Y Gong, J Zhang, J Zhang… - Frontiers in …, 2023 - frontiersin.org
Head and neck squamous cell carcinoma (HNSCC), as a complex and variable malignancy,
poses a significant threat to human health. Since the intricate association between HPV and …

The role of dendritic cells in radiation-induced immune responses

AP Kaur, A Alice, MR Crittenden, MJ Gough - International Review of Cell …, 2023 - Elsevier
Dendritic cells perform critical functions in bridging innate and adaptive immunity. Their
ability to sense adjuvant signals in their environment, migrate on maturation, and cross …

Tumor resident memory CD8 T cells and concomitant tumor immunity develop independently of CD4 help

TR Medler, G Kramer, S Bambina, AJ Gunderson… - Scientific Reports, 2023 - nature.com
Tissue resident memory (Trm) CD8 T cells infiltrating tumors represent an enriched
population of tumor antigen-specific T cells, and their presence is associated with improved …

Discovery of fluorinated 2‑Styryl 4 (3H)-quinazolinone as potential therapeutic hit for oral cancer

DP Satpute, U Shirwadkar, AK Tharalla… - Bioorganic & Medicinal …, 2023 - Elsevier
Oral squamous cell carcinoma (OSCC) is the most common malignant epithelial neoplasm,
affects the mouth and throat, and accounts for 90% of oral cancers. Considering the …

头颈部鳞状细胞癌免疫微环境及其作用机制的最新研究进展及展望

张少秋, 燕丽, 李瑞辰, 赵阳, 王孝深, 杨旭光… - 中国癌症 …, 2023 - china-oncology.com
头颈部恶性肿瘤(head and neck cancer, HNC) 作为一类常见的恶性肿瘤,
至今仍有较高的发病率和死亡率. 在HNC 中, 头颈部鳞状细胞癌(head and neck squamous-cell …

Recent advances and prospect in immune microenvironment and its mechanisms of function in head and neck squamous cell carcinoma

Z Shaoqiu, YAN Li, LI Ruichen, Z Yang… - China …, 2023 - china-oncology.com
Head and neck cancer (HNC) remains a significant cause of morbidity and mortality. The
most prevalent pathology among HNC is head and neck squamous cell carcinoma …