Exercise therapy for people with sarcopenic obesity: myokines and adipokines as effective actors

H Alizadeh Pahlavani - Frontiers in endocrinology, 2022 - frontiersin.org
Sarcopenic obesity is defined as a multifactorial disease in aging with decreased body
muscle, decreased muscle strength, decreased independence, increased fat mass, due to …

Muscle-to-tumor crosstalk: The effect of exercise-induced myokine on cancer progression

Q Huang, M Wu, X Wu, Y Zhang, Y Xia - Biochimica et Biophysica Acta …, 2022 - Elsevier
Physical exercise has gradually become a focus in cancer treatment due to its pronounced
role in reducing cancer risk, enhancing therapeutic efficacy, and improving prognosis. In …

Biochemical markers of musculoskeletal health and aging to be assessed in clinical trials of drugs aiming at the treatment of sarcopenia: consensus paper from an …

A Ladang, C Beaudart, JY Reginster… - Calcified Tissue …, 2023 - Springer
In clinical trials, biochemical markers provide useful information on the drug's mode of
action, therapeutic response and side effect monitoring and can act as surrogate endpoints …

Features of acute COVID-19 associated with post-acute sequelae of SARS-CoV-2 phenotypes: results from the IMPACC study

A Ozonoff, ND Jayavelu, S Liu, E Melamed… - Nature …, 2024 - nature.com
Post-acute sequelae of SARS-CoV-2 (PASC) is a significant public health concern. We
describe Patient Reported Outcomes (PROs) on 590 participants prospectively assessed …

Interplay of skeletal muscle and adipose tissue: sarcopenic obesity

MJ Park, KM Choi - Metabolism, 2023 - Elsevier
Sarcopenic obesity is becoming a global health concern, owing to the rising older
population, causing cardiometabolic morbidity and mortality. Loss of muscle exceeding …

The contribution of diet therapy and probiotics in the treatment of sarcopenia induced by prolonged immobilization caused by the COVID-19 pandemic

CD Nistor-Cseppento, TD Moga, AF Bungau, DM Tit… - Nutrients, 2022 - mdpi.com
The prolonged immobilization associated with COVID-19 infection and the restrictions
imposed by the pandemic have determined major changes in physical activity and eating …

Fibroblast growth factor 21 facilitates the homeostatic control of feeding behavior

CT Wu, AT Chaffin, KK Ryan - Journal of Clinical Medicine, 2022 - mdpi.com
Fibroblast growth factor 21 (FGF21) is a stress hormone that is released from the liver in
response to nutritional and metabolic challenges. In addition to its well-described effects on …

Potential therapeutic targets for sarcopenia identified by Mendelian randomisation

W Jiang, W Zhan, L Zhou, M Dong, L Liu, X Xu… - Age and …, 2023 - academic.oup.com
Background Identifying sarcopenia's causally associated plasma proteins would provide
potential therapeutic targets. Methods We screened out sarcopenia-related proteins with …

Fibroblast Growth Factor 21: A Fascinating Perspective on the Regulation of Muscle Metabolism

S Li, J Chen, P Wei, T Zou, J You - International Journal of Molecular …, 2023 - mdpi.com
Fibroblast growth factor 21 (FGF21) plays a vital role in normal eukaryotic organism
development and homeostatic metabolism under the influence of internal and external …

Sarcopenic obesity: epidemiology, pathophysiology, cardiovascular disease, mortality, and management

S Wei, TT Nguyen, Y Zhang, D Ryu… - Frontiers in …, 2023 - frontiersin.org
Sarcopenic obesity is defined as the coexistence of sarcopenia and obesity in the same
individual, characterized by of the co-presence of body fat accumulation and muscle loss …