Acromegaly: clinical features at diagnosis

L Vilar, CF Vilar, R Lyra, R Lyra, LA Naves - Pituitary, 2017 - Springer
Background Acromegaly is a rare and underdiagnosed disorder caused, in more than 95%
of cases, by a growth hormone (GH)-secreting pituitary adenoma. The GH hypersecretion …

The GH/IGF-1 axis in ageing and longevity

RK Junnila, EO List, DE Berryman, JW Murrey… - Nature Reviews …, 2013 - nature.com
Secretion of growth hormone (GH), and consequently that of insulin-like growth factor 1 (IGF-
1), declines over time until only low levels can be detected in individuals aged≥ 60 years …

Place of cabergoline in acromegaly: a meta-analysis

L Sandret, P Maison, P Chanson - The Journal of Clinical …, 2011 - academic.oup.com
Context: Cabergoline is widely considered to be poorly effective in acromegaly. Objective:
The aim of this study was to obtain a more accurate picture of the efficacy of cabergoline in …

Growth hormone, insulin-like growth factor-1, and the kidney: pathophysiological and clinical implications

P Kamenický, G Mazziotti, M Lombes… - Endocrine …, 2014 - academic.oup.com
Besides their growth-promoting properties, GH and IGF-1 regulate a broad spectrum of
biological functions in several organs, including the kidney. This review focuses on the renal …

Challenges in the diagnosis and management of acromegaly: a focus on comorbidities

A Abreu, AP Tovar, R Castellanos, A Valenzuela… - Pituitary, 2016 - Springer
Introduction Acromegaly is a rare, insidious disease resulting from the overproduction of
growth hormone (GH) and insulin-like growth factor 1 (IGF-1), and is associated with a range …

Endocrine aspects of obstructive sleep apnea

P Attal, P Chanson - The Journal of Clinical Endocrinology & …, 2010 - academic.oup.com
Context: Some endocrine and metabolic disorders are associated with a high frequency of
obstructive sleep apnea (OSA), and treatment of the underlying endocrine disorder can …

Acromegaly and mccune-albright syndrome

S Salenave, AM Boyce, MT Collins… - The Journal of Clinical …, 2014 - academic.oup.com
Background: McCune-Albright syndrome (MAS) includes the triad of poly/monostotic fibrous
dysplasia, café-au-lait spots, and hyperfunctioning endocrinopathies. Acromegaly affects …

Aging and dry eye disease

J Ding, DA Sullivan - Experimental gerontology, 2012 - Elsevier
Dry eye disease is a prevalent eye disorder that in particular affects the elderly population.
One of the major causes of dry eye, meibomian gland dysfunction (MGD), shows increased …

Screening for endocrine hypertension: an endocrine society scientific statement

WF Young Jr, DA Calhoun, JWM Lenders… - Endocrine …, 2017 - academic.oup.com
Hypertension may be the initial clinical presentation for at least 15 endocrine disorders. An
accurate diagnosis of endocrine hypertension provides clinicians with the opportunity to …

[PDF][PDF] Neuroendocrine regulation of growth hormone secretion

FJ Steyn, V Tolle, C Chen, J Epelbaum - Compr Physiol, 2016 - researchgate.net
This article reviews the main findings that emerged in the intervening years since the
previous volume on hormonal control of growth in the section on the endocrine system of the …