Molecular oxygen (O2) is essential for most biological reactions in mammalian cells. When
the intracellular oxygen content decreases, it is called hypoxia. The process of hypoxia is …

Ubiquitin-specific protease 14 (USP14), a deubiquitinating enzyme (DUB), is associated
with proteasomes and exerts a dual function in regulating protein degradation. USP14 …

Microglia become progressively activated and seemingly dysfunctional with age, and
genetic studies have linked these cells to the pathogenesis of a growing number of …

Oligodendrocyte precursor cells (OPCs) are not merely a transitory progenitor cell type, but
rather a distinct and heterogeneous population of glia with various functions in the …

Lipid droplets (LDs) are dynamic, cytosolic lipid‐storage organelles found in nearly all cell
types. Too many or too few LDs during excess or deficient fat storage lead to many different …

Our knowledge of inter-organellar communication has grown exponentially in recent years.
This review focuses on the interactions that cytoplasmic lipid droplets have with other …

Curcumin (diferuloylmethane), a yellow coloring agent extracted from turmeric is also used
as a remedy for the treatment and prevention of inflammatory diseases. Acute and chronic …

Steroid hormones are an important class of regulatory molecules that are synthesized in
steroidogenic cells of the adrenal, ovary, testis, placenta, brain, and skin, and influence a …

Lipid droplets (LDs) are ubiquitous cellular organelles for lipid storage which are composed
of a neutral lipid core bounded by a protein decorated phospholipid monolayer. Although …

Neurons are dependent on proper trafficking of lipids to neighboring glia for lipid exchange
and disposal of potentially lipotoxic metabolites, producing distinct lipid distribution profiles …