The nitric oxide pathway in pulmonary arterial hypertension: pathomechanism, biomarkers and drug targets

Z Lázár, A Bikov - Current Medicinal Chemistry, 2020 - ingentaconnect.com
The altered Nitric Oxide (NO) pathway in the pulmonary endothelium leads to increased
vascular smooth muscle tone and vascular remodelling, and thus contributes to the …

T-box protein 4 mutation causing pulmonary arterial hypertension and lung disease

A Maurac, É Lardenois, M Eyries… - European …, 2019 - Eur Respiratory Soc
Pulmonary arterial hypertension (PAH) is a progressive disease mainly characterised by a
widespread obstruction of distal pulmonary arteries [1]. Untreated, this disease rapidly leads …

[PDF][PDF] The shared pathogenesis of pulmonary artery hypertension

AB Hartopo, LK Dinarti - ACI (Acta Cardiologia Indonesiana), 2018 - journal.ugm.ac.id
Pulmonary artery hypertension is defined as an increased in pulmonary artery pressure
exceeding 25 mmHg with normal pulmonary wedge pressure. The pathogenesis of …

Primary and Secondary Pulmonary Hypertension

C Ginghină, R Enache - Right Heart Pathology: From Mechanism to …, 2018 - Springer
Pulmonary hypertension Pulmonary arterial hypertension (PAH) Pulmonary hypertension
(PH)(PH) is a complex syndrome that may complicate different cardiovascular, respiratory …

Congenital Heart Defects and Pulmonary Hypertension: The Heath–Edwards Paradigm

K Dimopoulos, E Orchard, A Angelini - Pulmonary Hypertension in Adult …, 2017 - Springer
Pulmonary hypertension (PH) is a haemodynamic and pathophysiological disorder
associated with a variety of cardiovascular and respiratory conditions, including congenital …