Molecular dynamics simulations of membranes and membrane proteins serve as
computational microscopes, revealing coordinated events at the membrane interface. As G …

The ongoing SARS-CoV-2 pandemic and the influenza epidemics have revived the interest
in understanding how these highly contagious enveloped viruses respond to alterations in …

Membrane fusion is a ubiquitous process associated with a multitude of biological events.
Although it has long been appreciated that membrane mechanics plays an important role in …

1Department of Biochemistry and Biophysics, University of Pennsylvania, Philadelphia, PA,
USA, 2Department of Biochemistry and Biophysics, Washington University in St. Louis, St …

Biological membranes are dynamic heterogeneous materials, and their shape and
organization are tightly coupled to the properties of the proteins in and around them …

The fusion peptide (FP) domain is necessary for the fusogenic activity of spike proteins in a
variety of enveloped viruses, allowing the virus to infect the host cell, and is the only part of …

The entry of influenza virus into the host cell requires fusion of its lipid envelope with the host
membrane. It is catalysed by viral hemagglutinin protein, whose fragments called fusion …

The fusion peptide of SARS-CoV-2 spike is essential for infection. How this charged and
hydrophobic domain occupies and affects membranes needs clarification. Its depth in …

SARS-CoV-2 is one of the most infectious viruses ever recorded. Despite a plethora of
research over the last several years, the viral life cycle is still not well understood …

We investigated the changes in internal flexibility of amyloid-β1–40 (Aβ) fibrils grown in the
presence of rat synaptic plasma vesicles. The fibrils are produced using a modified seeded …