Circuits and functions of the lateral habenula in health and in disease
H Hu, Y Cui, Y Yang - Nature Reviews Neuroscience, 2020 - nature.com
The past decade has witnessed exponentially growing interest in the lateral habenula (LHb)
owing to new discoveries relating to its critical role in regulating negatively motivated …
owing to new discoveries relating to its critical role in regulating negatively motivated …
Mechanisms of action and persistent neuroplasticity by drugs of abuse
ER Korpi, B den Hollander, U Farooq… - Pharmacological …, 2015 - ASPET
Adaptation of the nervous system to different chemical and physiologic conditions is
important for the homeostasis of brain processes and for learning and remembering …
important for the homeostasis of brain processes and for learning and remembering …
Diversity of transgenic mouse models for selective targeting of midbrain dopamine neurons
Ventral tegmental area (VTA) dopamine (DA) neurons have been implicated in reward,
aversion, salience, cognition, and several neuropsychiatric disorders. Optogenetic …
aversion, salience, cognition, and several neuropsychiatric disorders. Optogenetic …
Neuronal correlates of depression
D Chaudhury, H Liu, MH Han - Cellular and Molecular Life Sciences, 2015 - Springer
Major depressive disorder (MDD) is a common psychiatric disorder effecting approximately
121 million people worldwide and recent reports from the World Health Organization (WHO) …
121 million people worldwide and recent reports from the World Health Organization (WHO) …
Lateral preoptic control of the lateral habenula through convergent glutamate and GABA transmission
The lateral habenula (LHb) is a brain structure that participates in cognitive and emotional
processing and has been implicated in several mental disorders. Although one of the largest …
processing and has been implicated in several mental disorders. Although one of the largest …
Glial dysfunction in the mouse habenula causes depressive-like behaviors and sleep disturbance
The lateral habenula (LHb) regulates the activity of monoaminergic neurons in the
brainstem. This area has recently attracted a surge of interest in psychiatry because studies …
brainstem. This area has recently attracted a surge of interest in psychiatry because studies …
Increased metabolic potential, efficacy, and safety of emerging treatments in schizophrenia
JM Meyer, CU Correll - CNS drugs, 2023 - Springer
Patients with schizophrenia experience a broad range of detrimental health outcomes
resulting from illness severity, heterogeneity of disease, lifestyle behaviors, and adverse …
resulting from illness severity, heterogeneity of disease, lifestyle behaviors, and adverse …
Resting‐state functional connectivity of the human habenula in healthy individuals: Associations with subclinical depression
BA Ely, J Xu, WK Goodman, KA Lapidus… - Human brain …, 2016 - Wiley Online Library
Abstract Introduction: The habenula (Hb) is postulated to play a critical role in reward and
aversion processing across species, including humans, and has been increasingly …
aversion processing across species, including humans, and has been increasingly …
Review of the cytology and connections of the lateral habenula, an avatar of adaptive behaving
The cytology and connections of the lateral habenula (LHb) are reviewed. The habenula is
first introduced, after which the cytology of the LHb is discussed mainly with reference to cell …
first introduced, after which the cytology of the LHb is discussed mainly with reference to cell …
Sex differences in neuronal activation during aversion‐resistant alcohol consumption
ME Arnold, AN Butts, TR Erlenbach… - Alcohol: Clinical and …, 2023 - Wiley Online Library
Background One of the DSM‐5 criteria for Alcohol Use Disorder is continued alcohol
consumption despite negative consequences. This has been modeled in mice using …
consumption despite negative consequences. This has been modeled in mice using …