Glial and neuronal control of brain blood flow

D Attwell, AM Buchan, S Charpak, M Lauritzen… - Nature, 2010 - nature.com
Blood flow in the brain is regulated by neurons and astrocytes. Knowledge of how these
cells control blood flow is crucial for understanding how neural computation is powered, for …

Imaging brain development: the adolescent brain

SJ Blakemore - Neuroimage, 2012 - Elsevier
The past 15years has seen a rapid expansion in the number of studies using neuroimaging
techniques to investigate maturational changes in the human brain. In this paper, I review …

The social brain in adolescence

SJ Blakemore - Nature Reviews Neuroscience, 2008 - nature.com
The term'social brain'refers to the network of brain regions that are involved in
understanding others. Behaviour that is related to social cognition changes dramatically …

A default mode of brain function: a brief history of an evolving idea

ME Raichle, AZ Snyder - Neuroimage, 2007 - Elsevier
The concept of a default mode of brain function arose out of a focused need to explain the
appearance of activity decreases in functional neuroimaging data when the control state …

Global and local fMRI signals driven by neurons defined optogenetically by type and wiring

JH Lee, R Durand, V Gradinaru, F Zhang, I Goshen… - Nature, 2010 - nature.com
Despite a rapidly-growing scientific and clinical brain imaging literature based on functional
magnetic resonance imaging (fMRI) using blood oxygenation level-dependent (BOLD) …

Brain work and brain imaging

ME Raichle, MA Mintun - Annu. Rev. Neurosci., 2006 - annualreviews.org
Functional brain imaging with positron emission tomography and magnetic resonance
imaging has been used extensively to map regional changes in brain activity. The signal …

Glial regulation of the cerebral microvasculature

C Iadecola, M Nedergaard - Nature neuroscience, 2007 - nature.com
The brain is a heterogeneous organ with regionally varied and constantly changing
energetic needs. Blood vessels in the brain are equipped with control mechanisms that …

Astrocyte-mediated control of cerebral blood flow

T Takano, GF Tian, W Peng, N Lou, W Libionka… - Nature …, 2006 - nature.com
Local increase in blood flow during neural activity forms the basis for functional brain
imaging, but its mechanism remains poorly defined. Here we show that cortical astrocytes in …

Translational principles of deep brain stimulation

ML Kringelbach, N Jenkinson, SLF Owen… - Nature Reviews …, 2007 - nature.com
Deep brain stimulation (DBS) has shown remarkable therapeutic benefits for patients with
otherwise treatment-resistant movement and affective disorders. This technique is not only …

[PDF][PDF] Role of astrocytes in neurovascular coupling

GC Petzold, VN Murthy - Neuron, 2011 - cell.com
Neural activity is intimately tied to blood flow in the brain. This coupling is specific enough in
space and time that modern imaging methods use local hemodynamics as a measure of …