Although fire is now rarely used in synthetic chemistry, it was not until Robert Bunsen
invented the burner in 1855 that the energy from this heat source could be applied to a …

Microwave irradiation has been successfully applied in organic chemistry. Spectacular
accelerations, higher yields under milder reaction conditions and higher product purities …

A general aim of transition metal-catalysed organic synthesis is carbon–carbon (C–C) bond
formation. In this respect, the Pd-catalysed Suzuki–Miyaura (SM) coupling reaction 1 is one …

Since 1986, when Gedye and Giguere published their first articles in Tetrahedron Letters on
microwave assisted syntheses in household microwave ovens, there has been a steadily …

Tailored to the needs of medicinal and natural products chemists, the second edition of this
unique handbook brings the contents up to speed, almost doubling the amount of chemical …

Within the past decade, green chemistry has attained the status of a major scientific
discipline. 1, 2 The investigation and application of green chemistry principles has led to the …

In the past few years, using microwave energy to heat and drive chemical reactions has
become increasingly popular in the medicinal chemistry community. First described 20 years …

The question “why should microwave chemistry be green?” is evaluated in the context of the
twelve principles of green chemistry, with a focus on the 6th principle: design for energy …

Imidazole and benzimidazole systems are presented in a large number of common
therapeutics agents. They were widely used in organic and medicinal chemistry, but recently …

Direct and rapid heating by microwave irradiation in combination with sealed vessel
processing in many cases enables reactions to be carried out in a fraction of the time …