[HTML][HTML] Flavonoids as an effective sensitizer for anti-cancer therapy: Insights into multi-faceted mechanisms and applicability towards individualized patient profiles

A Liskova, M Samec, L Koklesova, A Brockmueller… - Epma Journal, 2021 - Springer
Cost-efficacy of currently applied treatments is an issue in overall cancer management
challenging healthcare and causing tremendous economic burden to societies around the …

Targeting monocarboxylate transporters (MCTs) in cancer: How close are we to the clinics?

M Singh, J Afonso, D Sharma, R Gupta, V Kumar… - Seminars in Cancer …, 2023 - Elsevier
As a result of metabolic reprogramming, cancer cells display high rates of glycolysis,
causing an excess production of lactate along with an increase in extracellular acidity …

[HTML][HTML] Therapeutic potential and main methods of obtaining selenium nanoparticles

EG Varlamova, EA Turovsky, EV Blinova - International Journal of …, 2021 - mdpi.com
This review presents the latest data on the importance of selenium nanoparticles in human
health, their use in medicine, and the main known methods of their production by various …

[HTML][HTML] The Antimicrobial, Antioxidant, and Anticancer Activity of Greenly Synthesized Selenium and Zinc Composite Nanoparticles Using Ephedra aphylla Extract

MM El-Zayat, MM Eraqi, H Alrefai, AY El-Khateeb… - Biomolecules, 2021 - mdpi.com
The current work aimed to synthesize selenium and zinc nanoparticles using the aqueous
extract of Ephedra aphylla as a valuable medicinal plant. The prepared nanoparticles were …

[HTML][HTML] Novel doxorubicin/folate-targeted trans-ferulic acid-loaded PLGA nanoparticles combination: In-vivo superiority over standard chemotherapeutic regimen for …

SA Helmy, S El-Mofty, AM El Gayar… - Biomedicine & …, 2022 - Elsevier
Abstract Aim Doxorubicin/Cyclophosphamide (AC) is one of the standard adjuvant
anthracycline-containing regimens that is still in use for breast cancer treatment. Cancer cell …

[HTML][HTML] Latent potential of multifunctional selenium nanoparticles in neurological diseases and altered gut microbiota

H Ashraf, D Cossu, S Ruberto, M Noli, S Jasemi… - Materials, 2023 - mdpi.com
Neurological diseases remain a major concern due to the high world mortality rate and the
absence of appropriate therapies to cross the blood–brain barrier (BBB). Therefore, the …

FTIR spectroscopic investigations of protein conformation provide clues of radioadaptation in the kidney of low-dose irradiated rats

A Abouelsayed, GS El-Bahy, AB Abdelrazzak - Journal of Molecular …, 2024 - Elsevier
Proteins comprise almost half of the weight of plasma membrane and are responsible for
preforming various membrane functions. Functionality of the protein is sensitive to its …

Indole-3-carbinol as a radiosensitizer and modulator of IR-dependent stemness in triple-negative breast cancer

ZS Eissa, MI Rady, MA Khalifa… - Egyptian Journal of …, 2024 - Taylor & Francis
Breast cancer (BC) is one of the most common malignant tumors among women worldwide
that contributes to the high mortality rate among other malignancies. The resistance …

[PDF][PDF] Impact of the phytochemicals cocktail “breast safeguard” in regulating the interplay between redox signalling and murine adenocarcinoma cell proliferation …

ME Abdraboh, DS Daw, AM AbouEl-Ezz, WM El-Kholy - Heliyon, 2021 - cell.com
Phytochemicals are natural plant extracts with a potent antioxidant, anti-inflammatory and
anticancer characteristics by acting as a cell signalling modulator. This study aims to …

The prophylactic and therapeutic effects of the phytochemical combination breast safeguard on Ehrlich cell progression

H Alwasify, YM El-Far… - Journal of Environmental …, 2021 - joese.journals.ekb.eg
2 million new cases in 2019. Phytochemicals have been used in traditional medicine for
centuries, however, they recently gained attention in cancer research due to their potent …