[HTML][HTML] P-21 activated kinases in liver disorders
Simple Summary Liver disorders, particularly liver cancer and hepatitis, are considered
major public health challenges. Nearly 90% of patients with liver cancer are diagnosed at …
major public health challenges. Nearly 90% of patients with liver cancer are diagnosed at …
Dissecting T-cell heterogeneity in esophageal squamous cell carcinoma reveals the potential role of LAIR2 in antitumor immunity
P Wang, W Zhuang, Z Zheng, L Zhang… - Clinical and …, 2023 - academic.oup.com
Esophageal squamous cell carcinoma (ESCC), one of the most commonly diagnosed and
lethal malignant diseases, has a complex tumor ecosystem. An obvious requirement for T …
lethal malignant diseases, has a complex tumor ecosystem. An obvious requirement for T …
Therapeutic targeting of TNIK in papillary thyroid carcinoma: a novel approach for tumor growth suppression
R Zhang, Y Yu, Y Yang, M Zhang, X Zhang, Y Chang… - Medical Oncology, 2024 - Springer
Papillary thyroid carcinoma (PTC) is a common endocrine malignancy. The pathology of
PTC is far from clear. As a kinase that can be targeted, the role of TNIK in PTC has not been …
PTC is far from clear. As a kinase that can be targeted, the role of TNIK in PTC has not been …
[HTML][HTML] Scinderin promotes glioma cell migration and invasion via remodeling actin cytoskeleton
X Lin, Z Zhao, SP Sun, W Liu - World Journal of Clinical Oncology, 2024 - ncbi.nlm.nih.gov
BACKGROUND Glioma is one of the most common intracranial tumors, characterized by
invasive growth and poor prognosis. Actin cytoskeletal rearrangement is an essential event …
invasive growth and poor prognosis. Actin cytoskeletal rearrangement is an essential event …
[HTML][HTML] The Rac inhibitor HV-107 as a potential therapeutic for metastatic breast cancer
GV Crespo, J Ortiz, EH O'Farrill, CP Vlaar… - Molecular …, 2023 - Springer
Background The significant challenge in treating triple-negative breast cancer (TNBC) lies in
its high rate of distant metastasis. To address this, inhibiting metastasis formation in TNBC is …
its high rate of distant metastasis. To address this, inhibiting metastasis formation in TNBC is …
PROTEOMIC APPROACHES TO IDENTIFY UNIQUE AND SHARED SUBSTRATES AMONG KINASE FAMILY MEMBERS
CL Howarth - 2023 - digitalcommons.dartmouth.edu
Protein phosphorylation is a reversible post-translational modification that is a critical
component of almost all signaling pathways. Kinases regulate substrate proteins through …
component of almost all signaling pathways. Kinases regulate substrate proteins through …