Follicular lymphoma

A Carbone, S Roulland, A Gloghini, A Younes… - Nature reviews Disease …, 2019 - nature.com
Follicular lymphoma (FL) is a systemic neoplasm of the lymphoid tissue displaying germinal
centre (GC) B cell differentiation. FL represents~ 5% of all haematological neoplasms and …

Follicular lymphoma: 2020 update on diagnosis and management

A Freedman, E Jacobsen - American journal of hematology, 2020 - Wiley Online Library
Disease overview Follicular lymphoma (FL) is generally an indolent B cell
lymphoproliferative disorder of transformed follicular center B cells. Follicular lymphoma is …

Four versus six cycles of CHOP chemotherapy in combination with six applications of rituximab in patients with aggressive B-cell lymphoma with favourable prognosis …

V Poeschel, G Held, M Ziepert, M Witzens-Harig… - The Lancet, 2019 - thelancet.com
Background Six cycles of R-CHOP (rituximab plus cyclophosphamide, doxorubicin,
vincristine, and prednisone) are the standard treatment for aggressive B-cell non-Hodgkin …

[HTML][HTML] Newly diagnosed and relapsed follicular lymphoma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up†☆

M Dreyling, M Ghielmini, S Rule, G Salles… - Annals of …, 2021 - annalsofoncology.org
Diagnosis should be based on a surgical specimen/excisional lymph node (LN) biopsy.
Core biopsies should only be carried out in patients without easily accessible LNs (eg …

Sustained progression-free survival benefit of rituximab maintenance in patients with follicular lymphoma: long-term results of the PRIMA study

E Bachy, JF Seymour, P Feugier, F Offner… - Journal of Clinical …, 2019 - ascopubs.org
PURPOSE The PRIMA study (ClinicalTrials. gov identifier: NCT00140582) established that 2
years of rituximab maintenance after first-line immunochemotherapy significantly improved …

[HTML][HTML] Follicular lymphoma in the modern era: survival, treatment outcomes, and identification of high-risk subgroups

CL Batlevi, F Sha, A Alperovich, A Ni, K Smith… - Blood cancer …, 2020 - nature.com
Patients with follicular lymphoma (FL) frequently require multiple treatments during their
disease course; however, survival based on lines of treatment remains poorly described in …

Follicular lymphoma: 2023 update on diagnosis and management

E Jacobsen - American Journal of Hematology, 2022 - Wiley Online Library
Abstract Disease Overview Follicular lymphoma (FL) is generally an indolent B cell
lymphoproliferative disorder of transformed follicular center B cells. FL is characterized by …

Response-adapted postinduction strategy in patients with advanced-stage follicular lymphoma: the FOLL12 study

S Luminari, M Manni, S Galimberti, A Versari… - Journal of Clinical …, 2022 - ascopubs.org
PURPOSE We compared 2 years of rituximab maintenance (RM) with a response-adapted
postinduction approach in patients with follicular lymphoma who responded to induction …

Rituximab and the risk of transformation of follicular lymphoma: a retrospective pooled analysis

M Federico, MDC Barrigón, L Marcheselli… - The Lancet …, 2018 - thelancet.com
Background Histological transformation of follicular lymphoma to aggressive lymphoma is a
serious event with a substantial effect on patient outcome. The aim of the Aristotle study was …

The oral PI3Kδ inhibitor Linperlisib for the treatment of relapsed and/or refractory follicular lymphoma: a phase II, single-arm, open-label clinical trial

T Wang, X Sun, L Qiu, H Su, J Cao, Z Li, Y Song… - Clinical Cancer …, 2023 - AACR
Purpose: To investigate the efficacy and safety of the novel orally active PI3Kδ inhibitor in
relapsed and/or refractory patients with follicular lymphoma (FL) who had received at least …